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CLCN4 / CLC-4

chloride channel, voltage-sensitive 4

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.

Gene Name: chloride channel, voltage-sensitive 4
Family/Subfamily: Ion Channel , Chloride channel - CLC
Synonyms: CLCN4, ClC-4, Chloride channel 4, Chloride channel protein 4, Chloride transporter ClC-4, ClC-4A, CLC4
Target Sequences: NM_001830 NP_001821.2 P51793

☰ Filters
Antibodies (21)
Proteins (2)
Over-Expression Lysate (2)
Primary (21)
CLCN4 / CLC-4 (23)
Human (21)
Mouse (10)
Rat (10)
Bovine (1)
Chicken (1)
Monkey (1)
Zebrafish (1)
WB (21)
ELISA (10)
ICC (5)
IF (12)
Peptide-ELISA (2)
rabbit (21)
IgG (13)
polyclonal pc (21)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (13)
aa663-689 (7)
N-Terminus (4)
C-Terminus (2)
190-270 aa, Internal (1)
Glu254 (1)
Internal (1)
aa221-270 (1)
No (23)
Myc-DDK (Flag) (2)
Human (1)
293T Cells (1)
HEK 293 Cells (1)
CLCN4 / CLC-4 Antibody - Western blot of CLC-4 (E254) pAb in extracts from MCF-7 cells.
Select
CLCN4 / CLC-4 Antibody (Glu254) LS-C177360
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (Glu254) Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$321; 100 µl/$403
CLCN4 / CLC-4 Antibody - Western blot of CLC-4 antibody
Select
CLCN4 / CLC-4 Antibody (190-270 aa, Internal) LS-C382745
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (190-270 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CLCN4 / CLC-4 Antibody - Western blot analysis of CLCN4 expression in MDAMB453 (A) whole cell lysates.
Select
CLCN4 / CLC-4 Antibody (Internal) LS-C352009
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (Internal) Antibody
Zebrafish, Rat, Mouse, Bovine, Human, Monkey
WB
Unconjugated
100 µl/$299
Select
CLCN4 / CLC-4 Antibody (aa663-689) LS-C330379
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (aa663-689) Antibody
Human
ELISA, IF, WB
Unconjugated
200 µl/$734
Select
CLCN4 / CLC-4 Antibody (aa663-689, Biotin) LS-C276297
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (aa663-689) (Biotin) Antibody
Human
ELISA, ICC, IF, WB
Biotin Conjugated
200 µl/$952
Select
CLCN4 / CLC-4 Antibody (aa663-689, FITC) LS-C276300
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (aa663-689) (FITC) Antibody
Human
ELISA, ICC, IF, WB
FITC Conjugated
200 µl/$952
Select
CLCN4 / CLC-4 Antibody (aa663-689, Azide-free, HRP) LS-C276298
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (aa663-689) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
CLCN4 / CLC-4 Antibody (aa663-689, APC) LS-C276296
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (aa663-689) (APC) Antibody
Human
ELISA, ICC, IF, WB
APC Conjugated
200 µl/$952
Select
CLCN4 / CLC-4 Antibody (aa663-689, PE) LS-C276299
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (aa663-689) (PE) Antibody
Human
ELISA, ICC, IF, WB
PE Conjugated
200 µl/$952
CLCN4 / CLC-4 Antibody - Staining MCF-7 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
CLCN4 / CLC-4 Antibody LS-C804947
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CLCN4 / CLC-4 Antibody - Peptide - + Immunofluorescence analysis of HUVEC cells, using CLCN4 antibody.
Select
CLCN4 / CLC-4 Antibody LS-C823964
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
CLCN4 / CLC-4 Antibody - Retinae were collected from adult White Leghorn chicken and fixed in the eyecup for two hours in 4% Paraformaldehyde (in PBS). Retinae were then removed from the eyecups and incubated in 30% sucrose (in PBS) overnight. Retinal tissue was embedded and frozen in OCT compound and cut into ~15um sections on a cryotome. Sections were blocked in 5% normal goat serum (in 1%BSA/.1%saponin PBS) for one hour and then incubated at RT with 1:250 (1%BSA/.1% saponin PBS) ClC4 antibody for 1 hour. Sections were then washed in PBS (3X10minutes) and then treated with secondary antibody (1:500 Cy3) for one hour. After another PBS wash series, sections were coverslipped and antibody labeling was visualized at 20X with a Leica upright microscope using a TRITC filter set and Xenon LAMP illumination. (Crousillac et al, 2003)
Select
CLCN4 / CLC-4 Antibody (aa663-689) LS-C100107
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (aa663-689) Antibody
Chicken, Human
IF, WB
Unconjugated
400 µl/$393
CLCN4 / CLC-4 Antibody - Immunofluorescence analysis of HUVEC cells, using CLCN4 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
CLCN4 / CLC-4 Antibody (aa221-270) LS-C119846
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (aa221-270) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
CLCN4 / CLC-4 Antibody (C-Terminus) LS-C6129
CLCN4 / CLC-4 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µl/$801
Select
CLCN4 / CLC-4 Antibody (C-Terminus) LS-C6130
CLCN4 / CLC-4 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$832
CLCN4 / CLC-4 Antibody - Western blot of CLCN4 Antibody with human 721_B Whole Cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CLCN4 / CLC-4 Antibody (N-Terminus) LS-C345322
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CLCN4 / CLC-4 Antibody - Western blot of CLCN4 Antibody with human 721_B Whole Cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CLCN4 / CLC-4 Antibody (N-Terminus, HRP) LS-C480180
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
CLCN4 / CLC-4 Antibody - Western blot of CLCN4 Antibody with human 721_B Whole Cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CLCN4 / CLC-4 Antibody (N-Terminus, Biotin) LS-C480178
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
CLCN4 / CLC-4 Antibody - Western blot of CLCN4 Antibody with human 721_B Whole Cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CLCN4 / CLC-4 Antibody (N-Terminus, FITC) LS-C480179
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
CLCN4 / CLC-4 Antibody - Western blot analysis of extracts of various cell lines, using CLCN4 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
Select
CLCN4 / CLC-4 Antibody LS-C748818
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CLCN4 / CLC-4 Antibody - Anti-CHML Antibody at 1:1000 dilution + H.skeletal muscle tissue lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 74 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Select
CLCN4 / CLC-4 Antibody LS-C356851
CLCN4 / CLC-4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$386
CLCN4 / CLC-4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
Human CLCN4 / CLC-4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75163
293T Cells
Myc-DDK (Flag)
84.7 kDa
20 µg/$215
CLCN4 / CLC-4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
CLCN4 / CLC-4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118384
HEK 293 Cells
Myc-DDK (Flag)
84.7 kDa
100 µg/$710
Viewing 1-23 of 23 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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