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| Catalog Number | Size | Price |
|---|---|---|
| LS-C124189-100 | 100 µg (0.1 mg/ml) | $862 |
Monoclonal Mouse anti‑Human CHRM2 / M2 Antibody (clone B8E5, aa168‑192, IHC, IF, WB) LS‑C124189
Monoclonal Mouse anti‑Human CHRM2 / M2 Antibody (clone B8E5, aa168‑192, IHC, IF, WB) LS‑C124189
Antibody:
CHRM2 / M2 Mouse anti-Human Monoclonal (aa168-192) (B8E5) Antibody
Application:
IHC, IHC-Fr, IF, WB, ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Pig, Sheep
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
CHRM2 / M2 Mouse anti-Human Monoclonal (aa168-192) (B8E5) Antibody
Application:
IHC, IHC-Fr, IF, WB, ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Pig, Sheep
Format:
Unconjugated, Unmodified
Specifications
Description
M2 antibody LS-C124189 is an unconjugated mouse monoclonal antibody to M2 (CHRM2) (aa168-192) from human. It is reactive with human, mouse, rat and other species. Validated for ELISA, IF, IHC and WB. Cited in 1 publication.
Target
Human CHRM2 / M2
Synonyms
CHRM2 | 7TM receptor | HM2 | M2 muscarinic receptor | M2-mAChR | Muscarinic receptor M2 | Muscarinic M2 receptor
Host
Mouse
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Pig, Sheep
(tested or 100% immunogen sequence identity)
Clonality
IgG2a
Monoclonal
Clone
B8E5
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Synthetic peptide corresponding to the second extracellular loop aa168-192, VRTVEDGECYIQFFSNAAVTFGTAI(C) of human muscarinic acetylcholine receptor M2. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Marmoset, Mouse, Rat, Sheep, Panda, Dog, Bovine, Horse, Pig, Guinea pig (100%); Elephant, Bat, Rabbit (96%); Hamster, Opossum, Platypus (92%); Xenopus (88%); Stickleback, Pufferfish, Zebrafish (84%); Turkey, Chicken (80%).
Epitope
aa168-192
Specificity
Recognizes the pentapeptide VRTVE (aa 168-172) corresponding to the N-terminal part of the second extracellular loop of the human M2 receptor. Species cross-reactivity: rat, mouse and guinea pig.
Applications
- IHC
- IHC - Frozen (1:50)
- Immunofluorescence (1:50)
- Western blot (1:50)
- ELISA (1:50)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry. ELISA: 1:50. Western Blot: 1:50 under non-reducing conditions. Immunohistochemistry (frozen): 1:50. Immunofluorescence: 1:50.
Presentation
PBS, 0.1% BSA
Storage
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CHRM2 / M2
LSBio Ratings
CHRM2 / M2 Antibody (aa168-192, clone B8E5) for IHC, IF/Immunofluorescence, WB/Western, ELISA LS-C124189 has an LSBio Rating of
Publications (4)
Learn more about The LSBio Ratings Algorithm
Publications (1)
Airway hyperresponsiveness induced by repeated esophageal infusion of HCl in guinea pigs. Cheng YM, Cao AL, Zheng JP, Wang HW, Sun YS, Liu CF, Zhang BB, Wang Y, Zhu SL, Wu DZ. American journal of respiratory cell and molecular biology. 2014 51:701-8. (WB; Human)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Pig, Rabbit, Sheep
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse, Rat, Guinea pig, Pig
Applications:
IHC, IHC - Frozen, Immunofluorescence, Western blot, Functional Assay
Species:
Human, Monkey, Bovine, Rabbit, Sheep
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Dog
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/16/2024
Date Requested: 4/16/2024
