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CHEMR23 / CMKLR1
chemokine-like receptor 1
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
| Gene Name: | chemokine-like receptor 1 |
| Family/Subfamily: | GPCR , Chemoattractant |
| Synonyms: | CMKLR1, Chemokine receptor-like 1, DEZ, CHEMERINR, Resolvin E1 receptor, RVER1, Chemokine-like receptor 1, ChemR23, G-protein coupled receptor DEZ |
| Target Sequences: | NM_004072 NP_004063.1 Q99788 |
Publications (3)
1
Specialized proresolution mediators in the bladder: annexin-A1 normalizes inflammation and bladder dysfunction during bladder outlet obstruction. Francis M Hughes Jr, Shelby N Harper, Brent D Nosé, Armand Allkanjari, Michael T Zheng, Huixia Jin, J Todd Purves. American journal of physiology. Renal physiology. 2021 October;321:F443-F454. [Full Text Article]
[PubMed:34396790]
[PMC:PMC8560402]
Related Antibodies: LS-B12924.
2
Specialized pro-resolution mediators in the bladder: Receptor expression and recovery of bladder function from cystitis. Francis M Hughes Jr, Armand Allkanjari, Michael R Odom, Huixia Jin, J Todd Purves. Experimental biology and medicine (Maywood, N.J.). 2022 April;247:700-711. [Full Text Article]
[PubMed:35044873]
[PMC:PMC9039492]
Related Antibodies: LS-B12924.
3
Up-regulation of CMKLR1 in endometriosis and its relationship with inflammatory responses. Zhe Zhang, Yumei Ding, Junjie Li, Shan Su. Histology and histopathology. 2022 September;18523. [Full Text Article]
[PubMed:36156768]
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CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Pig, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
Neuroscience
Fast Shipping
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ICC, IHC, IHC-P
Unconjugated
50 µg/$460
Neuroscience
Fast Shipping
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Dog, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
Fast Shipping
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
CHEMR23 / CMKLR1 Mouse anti-Human Monoclonal (1A7) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
100 µg/$617
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (Arg249) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (aa221-270) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (190-270 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CHEMR23 / CMKLR1 Rat anti-Mouse Monoclonal (1G10) Antibody
Mouse
IHC, IHC-Fr, IHC-P
Unconjugated
250 µg/$575
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (aa305-333) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (aa305-333) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (aa305-333) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (aa305-333) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (aa305-333) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (aa305-333) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µg/$386
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µg/$305; 100 µg/$357
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$386
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal (aa305-333) Antibody
Human
WB
Unconjugated
400 µl/$393
CHEMR23 / CMKLR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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