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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CFTR Antibody (aa25‑36) LS‑C152933
CFTR antibody LS-C152933 is an unconjugated mouse monoclonal antibody to CFTR from human, horse, pig and other species. Validated for ICC, IP and WB.
Antibody
Catalog
Size
Price
LS-C152933-100
100 µg (1 mg/ml)
$455

Popular CFTR Products

Antibody
Species: Human, Horse, Pig, Rabbit
Applications: IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Formalin-fixed, paraffin-embedded human pancreas stained with peroxidase-conjugate and AEC chromogen. Note membrane staining of epithelial cells in the intercalated ducts.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Immunoprecipitation
Antibody
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Immunoprecipitation
Formalin-fixed, paraffin-embedded human pancreas stained with peroxidase-conjugate and AEC chromogen. Note membrane staining of epithelial cells in the intercalated ducts.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Immunoprecipitation
Anti-CFTR antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.
Species: Human, Monkey, Bovine, Sheep
Applications: IHC, IHC - Paraffin

Product Description

CFTR antibody LS-C152933 is an unconjugated mouse monoclonal antibody to CFTR from human, horse, pig and other species. Validated for ICC, IP and WB.

Specifications

Target
Human CFTR
Synonyms
CFTR, ABC35, ABCC7, CF, DJ760C5.1, MRP7, CFTR/MRP, TNR-CFTR
Host
Mouse
Reactivity
Human, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Monkey, Bat, Bovine, Dog, Sheep, Chicken, Xenopus (at least 90% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • ICC
  • Western blot (10 µg/ml)
  • Immunoprecipitation
Failed Applications
  • IHC - Paraffin
Immunogen
CFTR antibody was raised against synthetic peptide (RKGYRQRLELSD) corresponding to residues 25-36 of human cystic fibrosis transmembrane conductance regulator (CFTR) Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Galago, Horse, Rabbit, Pig, Armadillo (100%); Orangutan, Marmoset, Ferret, Sheep, Cat, Bovine, Dog, Bat, Panda, Turkey, Chicken, Lizard, Xenopus (92%); Mouse, Rat, Hamster, Elephant, Zebra finch, Platypus (83%).
Epitope
aa25-36
Specificity
Human cystic fibrosis transmembrane conductance regulator (CFTR). Recognizes an epitope at the N-terminal between residues 24 and 35
Usage
Western blot: 10 ug/ml, recognizes CFTR (150-170kD) and two additional proteins at 52kD and 38kD. Immunoprecipitation. Immunofluorescence. Note: Does not work on paraffin embedded tissue.
Presentation
0.02 M PB, pH 7.6, 0.25 M NaCl, 0.1% Sodium Azide
Storage
Store at 4°C. Store undiluted.
Restrictions
For research use only.
About CFTR
CFTR (Cystic Fibrosis Transmembrane Conductance Regulator), sometimes also referred as ABCC7 (ATP-binding cassette, Subfamily C, Member 7), is a member of the ATP binding cassette (ABC) transporter family. CFTR functions as a chloride channel and controls the regulation of other transport pathways. P13569 NM_000492 NP_000483.3


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Requested From: United States
Date Requested: 10/15/2018

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