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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CFTR Antibody (aa2‑14) IHC‑plus™ LS‑B5115
Note: This antibody replaces LS-C113717
CFTR antibody LS-B5115 is an unconjugated goat polyclonal antibody to CFTR from human, bovine, monkey and other species. Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B5115-50
50 µg (0.5 mg/ml)
$425

Popular CFTR Products

Antibody
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Immunoprecipitation
Formalin-fixed, paraffin-embedded human pancreas stained with peroxidase-conjugate and AEC chromogen. Note membrane staining of epithelial cells in the intercalated ducts.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Immunoprecipitation
Formalin-fixed, paraffin-embedded human pancreas stained with peroxidase-conjugate and AEC chromogen. Note membrane staining of epithelial cells in the intercalated ducts.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Immunoprecipitation
Antibody
Species: Human, Horse, Pig, Rabbit
Applications: IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation

Product Description

CFTR antibody LS-B5115 is an unconjugated goat polyclonal antibody to CFTR from human, bovine, monkey and other species. Validated for IHC. Tested on 20 paraffin-embedded human tissues.
About CFTR
CFTR (Cystic Fibrosis Transmembrane Conductance Regulator), sometimes also referred as ABCC7 (ATP-binding cassette, Subfamily C, Member 7), is a member of the ATP binding cassette (ABC) transporter family. CFTR functions as a chloride channel and controls the regulation of other transport pathways. P13569 NM_000492 NP_000483.3

CFTR Antibody, ABC35 Antibody, ABCC7 Antibody, CF Antibody, DJ760C5.1 Antibody, MRP7 Antibody, CFTR/MRP Antibody, TNR-CFTR Antibody


Specifications

Target
Human CFTR
Host
Goat
Reactivity
Human, Monkey, Bovine, Sheep (tested or 100% immunogen sequence identity)
Predicted
Bat, Dog, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2.5 - 5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CFTR antibody was raised against synthetic peptide QRSPLEKASVVSK-C from the N-terminus of human CFTR (NP_000483.3). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Marmoset, Sheep, Bovine (100%); Galago, Ferret, Cat, Dog, Bat, Horse, Armadillo (92%); Pig, Guinea pig (85%).
Blocking Peptide
LS-E25852 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B5115. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa2-14
Specificity
Human CFTR.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Immunohistochemistry

Anti-CFTR antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.
Anti-CFTR antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.

Immunohistochemistry

Anti-CFTR antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.
Anti-CFTR antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.

Immunohistochemistry

Anti-CFTR antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.
Anti-CFTR antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.

Immunohistochemistry

Anti-CFTR antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.
Anti-CFTR antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.

Immunohistochemistry

Anti-CFTR antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.
Anti-CFTR antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.

Immunohistochemistry

Anti-CFTR antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.
Anti-CFTR antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.

Immunohistochemistry

Anti-CFTR antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.
Anti-CFTR antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.

Immunohistochemistry

Anti-CFTR antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.
Anti-CFTR antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5115 concentration 2.5 ug/ml.

Requested From: United States
Date Requested: 8/15/2018

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