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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CFL1 / Cofilin Antibody (aa4‑32, Biotin) LS‑C206444
Antibody
Cofilin antibody LS-C206444 is a biotin-conjugated rabbit polyclonal antibody to Cofilin (CFL1) from human and mouse. Validated for ELISA and WB.
Catalog
Size
Price
LS-C206444-200
200 µl
Unavailable

Popular CFL1 / Cofilin Products

Antibody
Species: Human, Monkey, Mouse, Rat
Applications: Western blot, ELISA
Antibody
Species: Human, Monkey, Mouse, Rat
Applications: Immunofluorescence, Western blot, ELISA
Anti-CFL1 / Cofilin antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2971 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-Cofilin antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7855 dilution 1:200.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Immunofluorescent analysis of Cofilin staining in K562 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 ??C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Species: Human, Mouse, Rat, Pig, Sheep, Zebrafish
Applications: ICC, Immunofluorescence, Western blot

Product Description

Cofilin antibody LS-C206444 is a biotin-conjugated rabbit polyclonal antibody to Cofilin (CFL1) from human and mouse. Validated for ELISA and WB.
About CFL1 / Cofilin
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. P23528 NM_005507 NP_005498.1

CFL1 Antibody, 18 kDa phosphoprotein Antibody, Cofilin Antibody, CFL Antibody, Cofilin 1 (non-muscle) Antibody, Cofilin, non-muscle isoform Antibody, p18 Antibody


Specifications

Target
Human CFL1 / Cofilin
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available conjugated with AP, APC, FITC, PE, HRP, .
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot
  • ELISA
  • (applications tested for the base form of this product only)
Epitope
aa4-32
Specificity
This CFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human CFL1.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.2, 0.09% sodium azide.
Storage
Short term: store at 4°C. Long term: aliquot and store -20°C for up to 6 months. Avoid freeze-thaw cycles. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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