Complement Factor B antibody LS-C44981 is an unconjugated mouse monoclonal antibody to human Complement Factor B (CFB). Validated for ELISA, Flow, IHC and WB.
Human CFB / Complement Factor B
(tested or 100% immunogen sequence identity)
Protein A purified
- IHC - Frozen
- Western blot
- Flow Cytometry
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Human factor B.
Recognizes the Bb fragment of 90 kD human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change which enables complement factor D to cleave the N-terminal of complement factor B, the Ba subunit, leaving the 63 kD Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation. Binds to both the Bb fragment and complement factor B so is not suitable for all ELISA applications.
ELISA: LS-C44981 binds to both the Bb fragment and complement factor B so is not suitable for all ELISA applications.
BBS, pH 8.4, 0.02% Sodium Azide
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
For research use only.
About CFB / Complement Factor B