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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CFB / Complement Factor B Antibody (N‑Terminus) LS‑C44981
Complement Factor B antibody LS-C44981 is an unconjugated mouse monoclonal antibody to human Complement Factor B (CFB). Validated for ELISA, Flow, IHC and WB.
Catalog
Size
Price
LS-C44981-100
100 µg (1 mg/ml)
$445
Description
Complement Factor B antibody LS-C44981 is an unconjugated mouse monoclonal antibody to human Complement Factor B (CFB). Validated for ELISA, Flow, IHC and WB.
Target
Human CFB / Complement Factor B
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Western blot
  • Flow Cytometry
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Human factor B.
Epitope
N-Terminus
Specificity
Recognizes the Bb fragment of 90 kD human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change which enables complement factor D to cleave the N-terminal of complement factor B, the Ba subunit, leaving the 63 kD Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation. Binds to both the Bb fragment and complement factor B so is not suitable for all ELISA applications.
Usage
ELISA: LS-C44981 binds to both the Bb fragment and complement factor B so is not suitable for all ELISA applications.
Presentation
BBS, pH 8.4, 0.02% Sodium Azide
Storage
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About CFB / Complement Factor B
P00751 NM_001710 NP_001701.2

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Requested From: United States
Date Requested: 12/11/2018
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