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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CENPI / CENP‑I Antibody (aa39‑88) LS‑C187203
CENP-I antibody LS-C187203 is an unconjugated rabbit polyclonal antibody to CENP-I (CENPI) from human, dog and horse. Validated for WB.
Catalog
Size
Price
LS-C187203-50
50 µg
$365

Popular CENPI / CENP-I Products

Antibody
Species: Human
Applications: Immunofluorescence, Western blot
Western blot of CENPI / CENP-I antibody.
Species: Mouse
Applications: IHC, Western blot
Western blot of recombinant CENPI / CENP-I.
Species: Human
Applications: IHC, Western blot
Western blot of CENPI / CENP-I antibody.
Species: Mouse
Applications: IHC, Western blot

Product Description

CENP-I antibody LS-C187203 is an unconjugated rabbit polyclonal antibody to CENP-I (CENPI) from human, dog and horse. Validated for WB.
About CENPI / CENP-I
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone. Q92674 NM_006733 NP_006724.2

CENPI Antibody, CENP-I Antibody, FSH primary response 1 Antibody, Mis6 Antibody, ICEN19 Antibody, LRPR1 Antibody, Centromere protein I Antibody, FSH primary response protein 1 Antibody, FSHPRH1 Antibody


Specifications

Target
Human CENPI / CENP-I
Host
Rabbit
Reactivity
Human, Dog, Horse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
CENPI / CENP-I antibody was raised against synthetic peptide located between aa39-88 of human CENPI (Q92674-2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon (100%); Monkey, Marmoset, Pig (92%); Dog, Horse (84%).
Blocking Peptide
LS-E19759 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C187203. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa39-88
Specificity
Human CENPI / CENP-I
Presentation
Lyophilized from PBS, 0.09% sodium azide, 2% sucrose
Reconstitution
Centrifuge the vial prior to opening. Reconstitute with sterile distilled water to a concentration of 1 mg/ml. Vortex and centrifuge again.
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Images

Western blot

Western blot of Human Thyroid Tumor. CENPI antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Thyroid Tumor. CENPI antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human Thyroid Tumor. CENPI antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Thyroid Tumor. CENPI antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human Thyroid Tumor. CENPI antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Thyroid Tumor. CENPI antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human Thyroid Tumor. CENPI antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human Thyroid Tumor. CENPI antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 9/25/2018

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