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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CENPA / CENP‑A Antibody (N‑Terminus, FITC) LS‑C448340
CENP-A antibody LS-C448340 is an FITC-conjugated rabbit polyclonal antibody to human CENP-A (CENPA). Validated for IHC and WB.
Catalog
Size
Price
LS-C448340-100
100 µl (1 mg/ml)
Unavailable

Popular CENPA / CENP-A Products

Antibody
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 10-20%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit, Zebrafish
Applications: Western blot
IHC of paraffin-embedded human breast carcinoma tissue, using Centromeric Protein A (Ab-7) Antibody. The picture on the right is treated with the synthesized peptide.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Immunohistochemical analysis of CENPA staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX. w
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Immunofluorescence, ELISA

Product Description

CENP-A antibody LS-C448340 is an FITC-conjugated rabbit polyclonal antibody to human CENP-A (CENPA). Validated for IHC and WB.
About CENPA / CENP-A
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro). P49450 NM_001809 NP_001800.1

CENPA Antibody, Centromere autoantigen A Antibody, Centromere-specific histone Antibody, CenH3 Antibody, Centromere protein A Antibody, Centromere protein A, 17kDa Antibody, CENP-A Antibody, Centromere protein A (17kD) Antibody


Specifications

Target
Human CENPA / CENP-A
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Gibbon, Monkey (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Fluorescein. Also available Unconjugated or conjugated with HRP, Biotin.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CENPA / CENP-A antibody was raised against synthetic peptide from N-Terminus of human CENPA (P49450, NP_001800). Percent identity by BLAST analysis: Human, Gorilla (100%); Gibbon, Monkey (92%); Panda (83%).
Epitope
N-Terminus
Specificity
Human CENPA
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS.
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

CENPA antibody LS-C80798 was used in IHC to stain formalin-fixed, paraffin-embedded human skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CENPA antibody LS-C80798 was used in IHC to stain formalin-fixed, paraffin-embedded human skin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 15%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 15%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

CENPA antibody LS-C80798 was used in IHC to stain formalin-fixed, paraffin-embedded human skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CENPA antibody LS-C80798 was used in IHC to stain formalin-fixed, paraffin-embedded human skin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 15%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 15%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

CENPA antibody LS-C80798 was used in IHC to stain formalin-fixed, paraffin-embedded human skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CENPA antibody LS-C80798 was used in IHC to stain formalin-fixed, paraffin-embedded human skin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 15%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 15%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

CENPA antibody LS-C80798 was used in IHC to stain formalin-fixed, paraffin-embedded human skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CENPA antibody LS-C80798 was used in IHC to stain formalin-fixed, paraffin-embedded human skin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 15%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 15%. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/22/2018

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