Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Gene Name: | CUGBP, Elav-like family member 3 |
Synonyms: | CELF3, CELF-3, CAG repeat protein 4, CAGH4, ETR-1, ERDA4, RNA-binding protein BRUNOL-1, TNRC4, Bruno-like protein 1, BRUNOL1, CAG repeat domain, CUG-BP and ETR-3 like factor 3 |
Target Sequences: | NM_007185 NP_009116.3 Q5SZQ8 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.