Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CELF2, BRUNOL3, CELF-2, Bruno-like protein 3, CUG-BP2, CUGBP2, ETR-3, HNAPOR, NAPOR, RNA-binding protein BRUNOL-3, NAPOR-2, ETR3
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Western blot (1:200 - 1:500)
CELF2 / CUGBP2 antibody was raised against recombinant fusion protein containing a sequence corresponding to amino acids 422-521 of human CELF2 (NP_006552.3). QQSAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY
Human CELF2 / CUGBP2
The predicted MW is 52kDa/54kDa/55kDa, while the observed MW by Western blot was 60kDa.
RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in embryonic, but not adult, skeletal muscle. Activates TNNT2 exon 5 inclusion by antagonizing the repressive effect of PTB.