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| Catalog Number | Size | Price |
|---|---|---|
| LS-B7134-0.1 | 0.1 mg (1 mg/ml) | $485 |
IHC‑plus™ Monoclonal Mouse anti‑Human CEACAM8 / CD66b Antibody (clone 80H3, IHC, WB) LS‑B7134
IHC‑plus™ Monoclonal Mouse anti‑Human CEACAM8 / CD66b Antibody (clone 80H3, IHC, WB) LS‑B7134
Note: This antibody replaces LS-C44340, LS-C44355
Antibody:
CEACAM8 / CD66b Mouse anti-Human Monoclonal (80H3) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB, Flo, Func
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
CEACAM8 / CD66b Mouse anti-Human Monoclonal (80H3) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB, Flo, Func
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
CD66b antibody LS-B7134 is an unconjugated mouse monoclonal antibody to human CD66b (CEACAM8). Validated for Flow, Func, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 4 publications.
Target
Human CEACAM8 / CD66b
Synonyms
CEACAM8 | CD66b antigen | Carcinoembryonic antigen CGM6 | CD67 | CD67 antigen | CGM6 | NCA-95 | CD66b
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
80H3
Conjugations
Unconjugated
Purification
Protein A purified from tissue culture supernatant
Modifications
Unmodified
Immunogen
CML leucocytes.
Specificity
Reacts with the CGM6 gene product of the carcinoembryonic gene family. This is a 95-100kD GPI anchored molecule. CD66b is expressed strongly by mature granulocytes and metamyelocytes, and weakly by bone marrow myelocytes. CD66b is not expressed by peripheral blood monocytes or lymphocytes.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- IHC - Frozen (1:25 - 1:100)
- Western blot
- Flow Cytometry (1:20 - 1:100)
- Functional Assay
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 5 x 10^5 cells or 100 ul whole blood.
Presentation
PBS, 0.09% Sodium Azide, 0.5% BSA
Storage
Upon receipt, aliquot and store at -20°C. May be stored at 4°C for up to 1 month. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CEACAM8 / CD66b
Validation
Anti-CEACAM8 / CD66b antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-CEACAM8 / CD66b antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
See More About...
LSBio Ratings
IHC-plus™ CEACAM8 / CD66b Antibody (clone 80H3) for IHC, WB/Western, Flow LS-B7134 has an LSBio Rating of
Publications (4.3)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (4)
Tumor-Infiltrating Immune Cells Are Associated With Prognosis of Gastric Cancer. Liu K, Yang K, Wu B, Chen H, Chen X, Chen X, Jiang L, Ye F, He D, Lu Z, Xue L, Zhang W, Li Q, Zhou Z, Mo X, Hu J. Medicine. 2015 94:e1631. (IHC; Human)
Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies. Hossain F, Al-Khami AA, Wyczechowska D, Hernandez C, Zheng L, Reiss K, Valle LD, Trillo-Tinoco J, Maj T, Zou W, Rodriguez PC, Ochoa AC. Cancer immunology research. 2015 3:1236-47. (IHC; Human)
The Differential Contribution of the Innate Immune System to a Good Pathological Response in the Breast and Axillary Lymph Nodes Induced by Neoadjuvant Chemotherapy in Women with Large and Locally Advanced Breast Cancers. Kaewkangsadan V, Verma C, Eremin JM, Cowley G, Ilyas M, Satthaporn S, Eremin O. Journal of immunology research. 2017 2017:1049023. (Human)
Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells. Al-Khami AA, Zheng L, Del Valle L, Hossain F, Wyczechowska D, Zabaleta J, Sanchez MD, Dean MJ, Rodriguez PC, Ochoa AC. Oncoimmunology. 2017 June;6:e1344804.
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Featured Products
Species:
Human
Applications:
Flow Cytometry, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Reactivity:
Human
Range:
15.6-1000 pg/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/15/2024
Date Requested: 4/15/2024
