(tested or 100% immunogen sequence identity)
Protein A/G purified
Also available Azide-free, Carrier-free
- IHC - Paraffin (1 - 2 µg/ml)
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Recombinant full-length human CEA protein. Antigen Molecular Weight: 80-200 kDa
This antibody recognizes proteins of 80-200 kDa , identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
Immunohistology (Formalin-fixed - 1-2 ug/ml for 30 min at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Store at 2°C to 8°C for up to 2 years.
For research use only. Intended for use by laboratory professionals.
This antibody carries the LSBio 100% Guarantee.