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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-C6028-100 100 µg $575 
Antibody

CEACAM 1+5+6+8 Antibody LS‑C6028

CEACAM 1+5+6+8 Antibody LS‑C6028

Antibody:
Mouse Monoclonal to Human CEACAM 1+5+6+8
Application:
IHC, WB, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$575 
LS-C6028-100
100 µg
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to Human CEACAM 1+5+6+8
Application:
IHC, WB, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
CEACAM 1+5+6+8 antibody LS-C6028 is an unconjugated mouse monoclonal antibody to human CEACAM 1+5+6+8. Validated for ELISA, Flow, IHC and WB.
Target
Human CEACAM 1+5+6+8
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • Flow Cytometry
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Immunization of BALB/c mice with CEA partially purified from a perchloric acid extract from liver metastases of colonic tumors (3).
Specificity
Broadly reactive antibody which reacts with most of the CEACAM molecules characterized to date (except CEACAM3, CEACAM4 and CEACAM7). Can be used to detect CEACAM1 (BGP/CD66a), CEACAM5 (CEA/CD66e), CEACAM6 (NCA/CD66c) and CEACAM8 (CGM6/CD66b) on transiently transfected BOSC23 cells by flow cytometry. Included and characterized in the studies from the VIth Leucocyte Typing Workshop.
Usage
Suitable for use in flow cytometry, cell-ELISA, ELISA, Western blots and immunohistology on cryosections. Specificity Testing: BOSC cells were transiently transfected with expression vectors containing either the cDNA of CEACAM1, 3, 5, 6, 7, 8 or a recombinant transmembrane-anchored PSG1 fusion protein. Recognition of CEACAM4 was tested on CHO cells stably transfected with a CEACAM4 expression vector. Expression of the constructs was confirmed with monoclonal antibodies known to recognize the corresponding proteins (CEACAM1, 3, 4, 5 and 6; CEACAM7; CEACAM8; PSG1. An irrelevant monoclonal antibody served as a negative control. For specificity testing, protein G purified antibody was tested on all CEACAM transfectants. A positive signal was obtained with CEACAM1, CEACAM5, CEACAM6 and CEACAM8 expressing cells.
Presentation
PBS, pH 7.2, 0.01% Sodium Azide
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Requested From: United States
Date Requested: 1/18/2020