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CDKN1A / WAF1 / p21 Antibody (clone WA1) LS‑C347464
P21 antibody LS-C347464 is an unconjugated mouse monoclonal antibody to p21 (CDKN1A / WAF1) from human, chimpanzee and monkey. Validated for ELISA, Flow, ICC, IHC and WB.
100 µg (1 mg/ml)

Popular CDKN1A / WAF1 / p21 Products

Species: Human, Mouse, Rat
Applications: IHC, Western blot, Immunoprecipitation
Formalin-fixed, paraffin-embedded human colon cancer stained with peroxidase-conjugate and AEC chromogen. Note nuclear staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Rat, Bovine
Applications: IHC, IHC - Paraffin, Immunoprecipitation
Immunohistochemistry Image
Species: Human
Applications: IHC, Western blot, ELISA
p21 antibody WA-1 immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Flow Cytometry
Western blot analysis of extracts of various cell lines.
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot

Product Description

P21 antibody LS-C347464 is an unconjugated mouse monoclonal antibody to p21 (CDKN1A / WAF1) from human, chimpanzee and monkey. Validated for ELISA, Flow, ICC, IHC and WB.
About CDKN1A / WAF1 / p21
CDKN1A / WAF1 / p21 is a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. P38936 NM_078467 NP_000380.1

CDKN1A Antibody, CDKN1 Antibody, CIP1 Antibody, CDK-interacting protein 1 Antibody, DNA synthesis inhibitor Antibody, p21CIP1 Antibody, MDA6 Antibody, PIC1 Antibody, SDI1 Antibody, WAF1 Antibody, CAP20 Antibody, CDK-interaction protein 1 Antibody, MDA-6 Antibody, p21 Antibody


Human CDKN1A / WAF1 / p21
Human, Chimpanzee, Monkey (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [WA1]
  • IHC
  • IHC - Paraffin
  • IHC - Frozen
  • ICC
  • Western blot
  • Flow Cytometry
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
WA1 is a mouse IgG1 monoclonal antibody derived from the fusion of SP2 mouse myeloma cells with splenocytes from a BALB/c mouse immunized with human p21 protein.
An epitope within the carboxy-terminal region of p21/WAF1.
p21/WAF1, also known as cip1 and cyclin-dependent kinase interacting protein 1, is a 21kD protein that belongs to the CDI family of cyclin-dependent kinase inhibitors. In humans p21/WAF1 is encoded by the CDKN1A gene, the transcription of which is regulated by P53, for example in the case of DNA damage. The p21/WAF1 protein exists within the nucleus as a complex with cyclin, cyclin-dependent kinase (cdk) and proliferating cell nuclear antigen (PCNA). It functions as a potent inhibitor of cyclin-dependent kinases and plays a critical role in regulating cell growth and the cellular response to DNA damage.
PBS, 0.09% sodium azide.
Store at 4°C, or in small aliquots at -20°C.
For research use only.
This antibody carries the LSBio 100% Guarantee.

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Date Requested: 6/18/2018

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