LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
CDKN1A / WAF1 / p21 Antibody (clone WA‑1) LS‑C358002
P21 antibody LS-C358002 is an unconjugated mouse monoclonal antibody to p21 (CDKN1A / WAF1) from human, mouse, rat and other species. Validated for Flow, IF and IHC.
Catalog
Size
Price
LS-C358002-20
20 µg
$255
LS-C358002-100
100 µg (0.2 mg/ml)
$395
Description
P21 antibody LS-C358002 is an unconjugated mouse monoclonal antibody to p21 (CDKN1A / WAF1) from human, mouse, rat and other species. Validated for Flow, IF and IHC.
Target
Human CDKN1A / WAF1 / p21
Host
Mouse
Reactivity
Human, Monkey, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [WA-1]
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified. Also available Ready-to-Use, Azide-free.
Applications
  • IHC
  • IHC - Paraffin (0.5 - 1 µg/ml)
  • Immunofluorescence (1 - 2 µg/ml)
  • Flow Cytometry (0.5 - 1 µg/10E6 cells)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Human recombinant protein.
Specificity
Human CDKN1A / WAF1 / p21
Usage
This antibody recognizes a 21kDa protein, identified as the p21 or p21WAF1 tumor suppressor protein. This antibody is highly specific and shows no cross-reaction with other closely related mitotic inhibitors. p21 is a specific inhibitor of cdk's and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. p21 expression is induced by the wild type, but not mutant, p53. Normal cells generally display a rather intense nuclear expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma). ELISA: Order BSA-free antibody format for coating.
Presentation
PBS, 0.1 mg/ml BSA, 0.05% Sodium Azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only.
About CDKN1A / WAF1 / p21
P38936 NM_078467 NP_000380.1

Popular CDKN1A / WAF1 / p21 Products

Formalin-fixed, paraffin-embedded human colon cancer stained with peroxidase-conjugate and AEC chromogen. Note nuclear staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Rat, Bovine
Applications: IHC, IHC - Paraffin, Immunoprecipitation
Western blot blot of extracts of various cell lines, using CDKN1A antibody.
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot
Immunohistochemistry Image
Species: Human
Applications: IHC, Western blot, ELISA
Formalin-fixed, paraffin-embedded bladder carcinoma stained with p21 antibody (HJ21).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Chimpanzee, Monkey, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Flow Cytometry

Publications (0)


Customer Reviews (0)


Images

Immunohistochemistry

p21 antibody WA-1 immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
p21 antibody WA-1 immunohistochemistry. This image was taken for the unmodified form of this product. Other forms have not been tested.

Immunohistochemistry

p21 antibody WA-1 immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
p21 antibody WA-1 immunohistochemistry. This image was taken for the unmodified form of this product. Other forms have not been tested.

Immunohistochemistry

p21 antibody WA-1 immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
p21 antibody WA-1 immunohistochemistry. This image was taken for the unmodified form of this product. Other forms have not been tested.

Immunohistochemistry

p21 antibody WA-1 immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
p21 antibody WA-1 immunohistochemistry. This image was taken for the unmodified form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/17/2018
Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy