LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
CDK5R1 Antibody (C‑Terminus, Biotin) LS‑C425771
CDK5R1 antibody LS-C425771 is a biotin-conjugated rabbit polyclonal antibody to CDK5R1 from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C425771-100
100 µl (1 mg/ml)
Unavailable

Popular CDK5R1 Products

Western blot of p35 (Q31) pAb in extracts from rat brain.
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot
Antibody
Species: Human
Applications: Immunofluorescence, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, ELISA
Immunofluorescent analysis of p35 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Species: Human, Mouse, Rat, Bovine, Zebrafish
Applications: ICC, Immunofluorescence, Western blot

Product Description

CDK5R1 antibody LS-C425771 is a biotin-conjugated rabbit polyclonal antibody to CDK5R1 from human, mouse, rat and other species. Validated for WB.
About CDK5R1
CDK5R1 (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5); the activation of CDK5 is required for proper development of the central nervous system. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form. The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions. P25 deregulates CDK5 activity by prolonging its activation and changing its cellular location. Q15078 NM_003885 NP_003876.1

CDK5R1 Antibody, CDK5R Antibody, CDK5P35 Antibody, p35 Antibody, p35nck5a Antibody, p23 Antibody, p25 Antibody, TPKII regulatory subunit Antibody, CDK5 activator 1 Antibody, NCK5A Antibody, Neuronal CDK5 activator Antibody


Specifications

Target
Mouse CDK5R1
Host
Rabbit
Reactivity
Mouse, Human, Chimpanzee, Rat, Bat, Bovine, Dog, Guinea pig, Horse (tested or 100% immunogen sequence identity)
Predicted
Monkey, Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
CDK5R1 antibody was raised against synthetic peptide from C-Terminus of mouse Cdk5r1 (P61809, NP_034001). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Galago, Marmoset, Mouse, Rat, Dog, Bovine, Bat, Elephant, Panda, Horse, Guinea pig (100%); Monkey, Pig (92%).
Epitope
C-Terminus
Specificity
Mouse CDK5R1 / p35
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS.
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Images


Western blot

CDK5R1 / p35 antibody LS-C145910 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CDK5R1 / p35 antibody LS-C145910 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

CDK5R1 / p35 antibody LS-C145910 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CDK5R1 / p35 antibody LS-C145910 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

CDK5R1 / p35 antibody LS-C145910 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CDK5R1 / p35 antibody LS-C145910 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

CDK5R1 / p35 antibody LS-C145910 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CDK5R1 / p35 antibody LS-C145910 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/22/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number