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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CDK5R1 Antibody (C‑Terminus, Azide‑free, HRP) LS‑C208337
CDK5R1 antibody LS-C208337 is an HRP-conjugated rabbit polyclonal antibody to human CDK5R1. Validated for ELISA, IHC and WB.
Antibody
Catalog
Size
Price
LS-C208337-200
200 µl
$680

Popular CDK5R1 Products

Immunofluorescent analysis of p35 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Species: Human, Mouse, Rat, Bovine, Zebrafish
Applications: ICC, Immunofluorescence, Western blot
Antibody
Species: Human
Applications: IHC, ELISA
Antibody
Species: Human
Applications: Immunofluorescence, Western blot, ELISA
Western blot of p35 (Q31) pAb in extracts from rat brain.
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

CDK5R1 antibody LS-C208337 is an HRP-conjugated rabbit polyclonal antibody to human CDK5R1. Validated for ELISA, IHC and WB.
About CDK5R1
CDK5R1 (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5); the activation of CDK5 is required for proper development of the central nervous system. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form. The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions. P25 deregulates CDK5 activity by prolonging its activation and changing its cellular location. Q15078 NM_003885 NP_003876.1

CDK5R1 Antibody, CDK5R Antibody, CDK5P35 Antibody, p35 Antibody, p35nck5a Antibody, p23 Antibody, p25 Antibody, TPKII regulatory subunit Antibody, CDK5 activator 1 Antibody, NCK5A Antibody, Neuronal CDK5 activator Antibody


Specifications

Target
Human CDK5R1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Horseradish Peroxidase. Also available Unconjugated or conjugated with AP, APC, Biotin, FITC, PE.
Purification
Protein G purified
Modifications
Azide-free. Also available Unmodified.
Applications
  • IHC
  • Western blot
  • ELISA
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Epitope
C-Terminus
Specificity
This CDK5R1(p35) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human CDK5R1(p35).
Usage
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.
Presentation
PBS, No preservatives added
Storage
Short term: store at 4°C. Long term: aliquot and store -20°C for up to 6 months. Avoid freeze-thaw cycles. Protect from light.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/20/2018

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