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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CDK3 Antibody (C‑Terminus, HRP) LS‑C481192
CDK3 antibody LS-C481192 is an HRP-conjugated rabbit polyclonal antibody to CDK3 from human, bovine, chimpanzee and other species. Validated for WB.
Catalog
Size
Price
LS-C481192-100
100 µl (0.65 mg/ml)
$385

Popular CDK3 Products

Western blot of CDK3 expression in transfected 293T cell line by CDK3 monoclonal antibody (M01), clone 3C12.
Species: Human
Applications: Western blot, ELISA
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with CDK3 Antibody (N-term Y19), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
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Species: Human
Applications: IHC, Western blot, Flow Cytometry
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Species: Mouse, Human
Applications: Western blot, ELISA
Immunohistochemistry of Human lung cancer using CDK3 Polyclonal Antibody at dilution of 1:30.
Species: Human, Mouse
Applications: IHC, ELISA

Product Description

CDK3 antibody LS-C481192 is an HRP-conjugated rabbit polyclonal antibody to CDK3 from human, bovine, chimpanzee and other species. Validated for WB.

Specifications

Target
Human CDK3
Synonyms
CDK3, Cell division protein kinase 3, Cell division kinase 3, Cyclin-dependent kinase 3
Host
Rabbit
Reactivity
Human, Chimpanzee, Bovine, Dog, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Horseradish Peroxidase. Also available Unconjugated or conjugated with Biotin, FITC.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
CDK3 antibody was raised against synthetic peptide from C-Terminus of human CDK3 (Q00526, NP_001249). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%); Monkey, Marmoset, Mouse (93%); Galago, Bat, Rabbit (87%); Dog (86%); Elephant, Bovine, Horse, Pig (81%); Panda, Slime mold (80%).
Epitope
C-Terminus
Specificity
Human CDK3
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
100 mM sodium phosphate, pH 7.6, 150 mM NaCl
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
About CDK3
Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Q00526 NM_001258 NP_001249.1


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Images

Western blot

Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 11/14/2018

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