CDC34

cell division cycle 34

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Cooperates with the E2 UBCH5C and the SCF(FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. Performs ubiquitin chain elongation building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin. UBE2D3 acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin. Cooperates with the SCF(SKP2) E3 ligase complex to regulate cell proliferation through ubiquitination and degradation of MYBL2 and KIP1. Involved in ubiquitin conjugation and degradation of CREM isoform ICERIIgamma and ATF15 resulting in abrogation of ICERIIgamma- and ATF5-mediated repression of cAMP-induced transcription during both meiotic and mitotic cell cycles. Involved in the regulation of the cell cycle G2/M phase through its targeting of the WEE1 kinase for ubiquitination and degradation. Also involved in the degradation of beta-catenin. Is target of human herpes virus 1 protein ICP0, leading to ICP0-dependent dynamic interaction with proteasomes.

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Products

Antibodies (23)

Proteins (6)

Type

Over-Expression Lysate (2)

Primary (23)

Recombinant (4)

Target

CDC34 (29)

Reactivity

Human (23)

Mouse (10)

Rat (6)

Bovine (3)

Monkey (4)

Application

IHC (3)

IHC-P (1)

WB (19)

ELISA (8)

IF (2)

IP (3)

Peptide-ELISA (2)

Host

rabbit (19)

mouse (4)

Product Group

IHCPlus (1)

Isotype

IgG (13)

IgG1 (2)

Clonality

monoclonal mc (3)

polyclonal pc (20)

Clone

14B5 (1)

90.12 (1)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Preservative Free (2)

Unconjugated (17)

Epitope

C-Terminus (4)

Internal (2)

111-160 aa, Internal (1)

Asp163 (1)

N-Terminus (1)

aa114-163 (1)

Publications

No (29)

Tag

6His, N-terminus (1)

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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IHC-plus™ CDC34 Antibody LS-B14894

(4.0) Rating

Antibody:

CDC34 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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CDC34 Antibody LS-C406295

Antibody:

CDC34 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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CDC34 Antibody LS-C664507

Antibody:

CDC34 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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CDC34 Antibody LS-C765420

Antibody:

CDC34 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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CDC34 Antibody (clone 14B5, Preservative Free) LS-C19945

Antibody:

CDC34 Mouse anti-Human Monoclonal (Preservative Free) (14B5) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$450

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CDC34 Antibody (clone 90.12, Preservative Free) LS-C19947

Antibody:

CDC34 Mouse anti-Human Monoclonal (Preservative Free) (90.12) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$450

Select

CDC34 Antibody LS-C742939

Antibody:

CDC34 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

CDC34 Antibody (111-160 aa, Internal) LS-C386950

Antibody:

CDC34 Rabbit anti-Human Polyclonal (111-160 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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CDC34 Antibody (aa114-163) LS-C199807

Antibody:

CDC34 Rabbit anti-Human Polyclonal (aa114-163) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

CDC34 Antibody LS-C807216

Antibody:

CDC34 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CDC34 Antibody (N-Terminus) LS-C83531

Antibody:

CDC34 Mouse anti-Human Monoclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$563

Select

CDC34 Antibody LS-C19954

Antibody:

CDC34 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$450

Select

CDC34 Antibody LS-C396135

Antibody:

CDC34 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

CDC34 Antibody (HRP) LS-C396148

Antibody:

CDC34 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

CDC34 Antibody (Biotin) LS-C396150

Antibody:

CDC34 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

CDC34 Antibody (FITC) LS-C396149

Antibody:

CDC34 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

CDC34 Antibody (C-Terminus) LS-C112299

Antibody:

CDC34 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

CDC34 Antibody (C-Terminus, HRP) LS-C481268

Antibody:

CDC34 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Bovine, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

CDC34 Antibody (C-Terminus, Biotin) LS-C481265

Antibody:

CDC34 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Bovine, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

CDC34 Antibody (C-Terminus, FITC) LS-C481266

Antibody:

CDC34 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Bovine, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

CDC34 Antibody (Asp163) LS-C177296

Antibody:

CDC34 Rabbit anti-Human Polyclonal (Asp163) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

CDC34 Antibody (Internal) LS-C351960

Antibody:

CDC34 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

CDC34 Antibody (Internal) LS-C413437

Antibody:

CDC34 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$321

Select

Human CDC34 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67279

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.6 kDa

Price:

20 µg/$1,107

Select

Human CDC34 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79462

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.6 kDa

Price:

20 µg/$150

Viewing 1-25 of 29 product results

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