CDC25B

cell division cycle 25B

CDC25B, a CDC25 dual specificity protein phosphatase, has been shown to affect cell cycle regulation by activating cyclin-dependent kinases Cdk1 and Cdk2 during G2 phase. CDC25B also has been shown to possess oncogenic properties and has been implicated in lung, breast, esophagus, stomach, ovarian, and other cancers. Recently CDC25B has been shown to be a steroid receptor coactivator and this function is independent of the protein phosphatase activity in vitro. CDC25B deficient mice are viable but the female mice are sterile due to the arrest of cell division in oocytes. At least five mRNA splice variants have been documented for CDC25B.

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Products

Antibodies (101)

Proteins (7)

ELISA Kits (3)

Type

Cell-Based Phosphorylation (2)

Custom (1)

Over-Expression Lysate (4)

Primary (101)

Recombinant (3)

Target

CDC25B (111)

Reactivity

Human (102)

Mouse (29)

Rat (22)

Bovine (3)

Chimpanzee (3)

Dog (6)

Guinea pig (6)

Horse (4)

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IHC (42)

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Host

rabbit (98)

mouse (3)

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IHCPlus (4)

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IgG (61)

IgG1,k (1)

IgG2b (2)

Clonality

monoclonal mc (4)

polyclonal pc (97)

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EPR3459(2) (1)

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Epitope

aa377-566 (8)

Ser353 (7)

aa165-194 (7)

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aa301-350 (4)

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260-340 aa (2)

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Internal (2)

aa421-567 (2)

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aa119-248 (1)

aa268-317 (1)

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aa541-559 (1)

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Publications

No (111)

Sample Type

Adherent Cell Cultures (2)

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GST (1)

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His (1)

Myc-DDK (Flag) (4)

Species

Human (5)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

IHC-plus™ CDC25B Antibody (Internal, clone EPR3459(2)) LS-B6243

(4.0) Rating

Antibody:

CDC25B Rabbit anti-Human Monoclonal (Internal) (EPR3459(2)) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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CDC25B Antibody (260-340 aa) LS-C380653

Antibody:

CDC25B Rabbit anti-Human Polyclonal (260-340 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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Human CDC25B Protein (Recombinant His) (aa377-566) - LS-G16315

Source:

E. coli

Tag:

His

Molecular Weight:

23.6 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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CDC25B Antibody (aa56-105) LS-B931

Antibody:

CDC25B Rabbit anti-Human Polyclonal (aa56-105) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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CDC25B Antibody (aa289-338) LS-C117556

Antibody:

CDC25B Rabbit anti-Human Polyclonal (aa289-338) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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CDC25B Antibody (N-Terminus) LS-C29916

Antibody:

CDC25B Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$424

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CDC25B Antibody (aa331-360, Biotin) LS-C254250

Antibody:

CDC25B Rabbit anti-Human Polyclonal (aa331-360) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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CDC25B Antibody LS-C498549

Antibody:

CDC25B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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CDC25B Antibody LS-C761169

Antibody:

CDC25B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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CDC25B Antibody (phospho-Ser353) LS-C808491

Antibody:

CDC25B Rabbit anti-Human Polyclonal (pSer353) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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CDC25B Antibody (phospho-Ser323) LS-C801073

Antibody:

CDC25B Rabbit anti-Human Polyclonal (pSer323) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CDC25B Antibody (p353) LS-C822244

Antibody:

CDC25B Rabbit anti-Human Polyclonal (p353) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

CDC25B Antibody LS-C417491

Antibody:

CDC25B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

CDC25B Antibody (aa319-368) LS-C117853

Antibody:

CDC25B Rabbit anti-Human Polyclonal (aa319-368) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

CDC25B Antibody (290-370 aa) LS-C382584

Antibody:

CDC25B Rabbit anti-Human Polyclonal (290-370 aa) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

IHC-plus™ CDC25B Antibody (aa165-194) LS-B9050

(4.0) Rating

Antibody:

CDC25B Rabbit anti-Human Polyclonal (aa165-194) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

Select

IHC-plus™ CDC25B Antibody (aa331-360) LS-B9049

(4.0) Rating

Antibody:

CDC25B Rabbit anti-Human Polyclonal (aa331-360) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

Select

CDC25B Antibody (Lys349) LS-C176399

Antibody:

CDC25B Rabbit anti-Human Polyclonal (Lys349) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

CDC25B Antibody LS-C664504

Antibody:

CDC25B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

CDC25B Antibody (phospho-Ser353) LS-C198777

Antibody:

CDC25B Rabbit anti-Human Polyclonal (pSer353) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

CDC25B Antibody LS-C417492

Antibody:

CDC25B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

CDC25B Antibody (Internal) LS-C353933

Antibody:

CDC25B Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

CDC25B Antibody (260-340 aa) LS-C382586

Antibody:

CDC25B Rabbit anti-Human Polyclonal (260-340 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

CDC25B Antibody LS-C801584

Antibody:

CDC25B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CDC25B Antibody (phospho-Ser187) LS-C327042

Antibody:

CDC25B Rabbit anti-Human Polyclonal (pSer187) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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