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Catalog Number Size Price
LS-C43995-100 100 Tests $456 
Antibody

Monoclonal Hamster anti‑Mouse CD81 Antibody (clone Eat2, RPE) LS‑C43995

Monoclonal Hamster anti‑Mouse CD81 Antibody (clone Eat2, RPE) LS‑C43995

Note: This antibody replaces LS-C57509
Antibody:
CD81 Hamster anti-Mouse Monoclonal (RPE) (Eat2) Antibody
Application:
Flo
Reactivity:
Mouse
Format:
R. Phycoerythrin, Unmodified
Other formats:
Price
Catalog Number
$456
LS-C43995-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
CD81 Hamster anti-Mouse Monoclonal (RPE) (Eat2) Antibody
Application:
Flo
Reactivity:
Mouse
Format:
R. Phycoerythrin, Unmodified
Other formats:

Specifications

Description
CD81 antibody LS-C43995 is an RPE-conjugated hamster monoclonal antibody to mouse CD81. Validated for Flow.
Target
Mouse CD81
Synonyms
CD81 | CD81 antigen | CD81 molecule | CVID6 | S5.7 | TAPA1 | TAPA-1 | Tetraspanin-28 | TSPAN28 | Tspan-28
Host
Hamster
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
Eat2
Conjugations
R. Phycoerythrin. Also available Unconjugated or conjugated with FITC.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
38C13, murine B cell line.
Specificity
Recognizes mouse and rat CD81, also known as TAPA-1 or Target of the antiproliferative antibody 1. CD81 is a 236 amino acid ~26 kD multipass transmembrane protein belonging to the TM4SF family. In rodents CD81 is expressed at much higher levels on resting B cells than on T cells, although increased expression on T cells is found following activation. Induces homotypic aggregation of B cells and inhibits anti Ig and IL-4 induced proliferation. Eat 2 requires the presence of both extracellular loops of TAPA-1 for binding. Mice lacking CD81 demonstrate reduced fertility through impaired oocyte-sperm fusion, double knockout CD81-/- CD9-/- mice are completely infertile suggesting complementary roles in oocyte-sperm fusion.
Applications
  • Flow Cytometry (1:1)
  • Applications tested for the base form of this product only
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Presentation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Reconstitution
Reconstitute with distilled water.
Storage
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CD81
P60033 NM_004356 NP_004347.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 8/10/2022