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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD81 Antibody (clone Eat2, FITC) LS‑C62534
Antibody
CD81 antibody LS-C62534 is an FITC-conjugated mouse monoclonal antibody to mouse CD81. Validated for Flow.
Catalog
Size
Price
LS-C62534-100
100 µg
Unavailable
LS-C62534-300
300 µg
Unavailable

Popular CD81 Products

Antibody
Species: Human
Applications: ICC, Western blot, Flow Cytometry
Frozen human tonsil stained with peroxidase-conjugate and AEC chromogen. Note cell membrane staining of lymphocytes.
Species: Human
Applications: IHC, IHC - Frozen, Immunofluorescence, Flow Cytometry
Immunohistochemistry of CD81 in human brain tissue with CD81 antibody at 2 µg/ml.
Species: Human, Mouse, Rat
Applications: IHC, Western blot, ELISA
Flow cytometry of CD81 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: ICC, Western blot, Flow Cytometry
Anti-CD81 antibody IHC of human tonsil, germinal center. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7347 dilution 1:50.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry

Product Description

CD81 antibody LS-C62534 is an FITC-conjugated mouse monoclonal antibody to mouse CD81. Validated for Flow.
About CD81
CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. P60033 NM_004356 NP_004347.1

CD81 Antibody, CD81 antigen Antibody, CD81 molecule Antibody, CVID6 Antibody, S5.7 Antibody, TAPA1 Antibody, TAPA-1 Antibody, Tetraspanin-28 Antibody, TSPAN28 Antibody, Tspan-28 Antibody


Specifications

Target
Mouse CD81
Host
Mouse
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [Eat2]
Conjugations
Fluorescein
Purification
Purified
Modifications
Unmodified
Applications
  • Flow Cytometry (1 µg/10E6 cells)
Specificity
reacts with the extracellular loops of murine CD81 (TAPA-1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4+CD8+ thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and NK cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81+/+ B cells to levels similar to that of CD81-/- B cells
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.02% sodium azide, EIA grade BSA.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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