Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse, Rat, Rodent
(tested or 100% immunogen sequence identity)
Protein G purified
CD81 antibody was raised against 38C13, murine B cell line.
Recognizes mouse and rat CD81, a 26kD cell surface glycoprotein that is also known as TAPA-1. In rodents CD81 is expressed at much higher levels on resting B cells than on T cells, although increased expression on T cells is found following activation. 3H1702 induces homotypic aggregation of B cells and inhibits anti Ig and IL-4 induced proliferation. 3H1702 requires the presence of both extracellular loops of TAPA-1 for binding. Species cross-reactivity: Mouse, rat.
Flow Cytometry: Neat. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
100 tst deionized water
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins.