Human CD74 / CLIP

Mouse

Human, Mouse (tested or 100% immunogen sequence identity)

IgG1,k Monoclonal

LN-2

Unconjugated

Protein G purified

Unmodified. Also available Azide-free, BSA-free, Ready-to-Use.

SU-DHL-4 lymphoma cells.

Human CD74

• IHC - Paraffin (1 µg/ml)
• Immunofluorescence (1 - 4 µg/ml)
• Flow Cytometry (0.5 - 1 µg/10E6 cells)
• ELISA

CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. CD74 antibody stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. antibody to CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+). ELISA: Order BSA-free format for coating.

0.2 mg/ml in 1x PBS with 0.1 mg/ml BSA (US Sourced) and 0.05% sodium azide

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P04233 NCBI: NM_004355 NP_004346.1