CD59 antibody LS-C392106 is an unconjugated mouse monoclonal antibody to human CD59. Validated for Flow, IF and IHC.
(tested or 100% immunogen sequence identity)
Protein G purified
Also available Ready-to-Use
- IHC - Paraffin (1 - 2 µg/ml)
- Immunofluorescence (1 - 2 µg/ml)
- Flow Cytometry (0.5 - 1 µg/10E6 cells)
- (applications tested for the base form of this product only)
See our complete line of Immunohistochemistry Reagents
including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
CD59 antibody was raised against recombinant Full-length Human Protein.
CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. [UniProt] Titering of the CD59 antibody may be required for optimal performance. FFPE testing requires sections to be boiled in pH6 10mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
0.01% BSA, 0.05% sodium azide
Store at 2°C to 8°C.
For research use only.