CD59

CD59 molecule, complement regulatory protein

CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

☰ Filters

Products

Antibodies (196)

Proteins (30)

ELISA Kits (17)

Type

Custom (1)

Over-Expression Lysate (11)

Primary (196)

Recombinant (19)

Sandwich (15)

Sandwich CLIA (1)

Target

CD59 (243)

Reactivity

Human (150)

Mouse (18)

Rat (27)

Baboon (1)

Chicken (1)

Crab-eating macaque (1)

Cynomolgus (1)

Guinea pig (1)

Monkey (10)

Pig (11)

Porcine (2)

Rabbit (12)

Rhesus monkey (1)

Sheep (1)

more less

Application

IHC (55)

IHC-Fr (9)

IHC-P (32)

WB (106)

Flo (95)

ELISA (32)

Func (9)

ICC (1)

IF (27)

IP (19)

RIA (1)

SDS-PAGE (1)

more less

Host

rabbit (97)

mouse (88)

guinea pig (3)

rat (8)

Product Group

IHCPlus (6)

PathPlus Cancer (2)

Isotype

IgG (50)

IgG1 (16)

IgG1,k (17)

IgG2a (23)

IgG2a,k (2)

IgG2b (20)

IgG2b,k (1)

IgM (2)

IgM,k (5)

Clonality

monoclonal mc (105)

polyclonal pc (89)

recombinant monoclonal rmc (2)

Clone

001 (2)

002 (1)

014 (4)

015 (1)

029 (1)

031 (1)

193-27 (2)

1F5 (5)

2E11B6 (1)

3G6 (1)

7A6 (2)

8D2B8 (2)

BRA-10G (7)

CDLA59-1 (3)

MACIF/1193 (3)

MACIF/2867R (2)

MACIF/629 (3)

MEM-129 (2)

MEM-43 (16)

MEM-43/5 (6)

OTI2E11 (2)

p282(H19) (1)

SPM616 (2)

TH9 (1)

WK8 (1)

YTH53.1 (2)

more less

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (2)

96-Well Strip Plate (14)

AF647 Conjugated (1)

APC (6)

APC Conjugated (14)

Azide-free (10)

Biotin Conjugated (19)

BSA-free (6)

Carrier-free (2)

Concentrated (2)

Cy3 Conjugated (6)

Cy7 Conjugated (6)

FITC Conjugated (26)

HRP Conjugated (12)

PE Conjugated (19)

PerCP Conjugated (1)

Preservative Free (7)

Ready-to-Use (3)

RPE Conjugated (4)

Unconjugated (88)

more less

Epitope

aa25-104 (11)

aa26-102 (10)

aa21-107 (8)

aa22-96 (8)

aa23-105 (8)

aa26-98 (8)

aa209-469 (2)

41-90 aa, Internal (1)

Amino Acid: 31-111 (1)

aa29-102 (1)

Publications

No (240)

Yes (3)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (10)

Serum (10)

Tissue Homogenates (2)

Urine (1)

Tag

6His, C-terminus (1)

6His, N-terminus (2)

Fc, C-terminus (1)

GST (2)

His (3)

His, N-terminus (1)

His,C-terminus (2)

His-S (5)

His-T7 (1)

Myc-DDK (Flag) (12)

Species

Human (22)

Mouse (3)

Pig (1)

Rabbit (1)

Rat (2)

Rhesus monkey (1)

Source

293T Cells (11)

E. coli (10)

HEK 293 Cells (5)

Human (1)

Human Cells (1)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (6)

Select

PathPlus™ CD59 Antibody (clone MEM-43) LS-B1852

Cancer

(5.0) Rating

(1) Publication(s)

Antibody:

CD59 Mouse anti-Human Monoclonal (MEM-43) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, IP

Format:

Unconjugated

Price:

0.05 mg/$460

Select

PathPlus™ CD59 Antibody (clone MEM-43/5) LS-B1853

Cancer

(5.0) Rating

Antibody:

CD59 Mouse anti-Human Monoclonal (MEM-43/5) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

0.05 mg/$460

Select

IHC-plus™ CD59 Antibody (clone 1F5) LS-B1619

(4.0) Rating

Antibody:

CD59 Mouse anti-Human Monoclonal (1F5) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

IHC-plus™ CD59 Antibody (clone p282(H19)) LS-B1960

(4.0) Rating

Antibody:

CD59 Mouse anti-Human Monoclonal (p282(H19)) Antibody

Reactivity:

Human, Monkey, Baboon

Applications:

Flo, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

CD59 Antibody (clone 8D2B8) LS-C169140

Antibody:

CD59 Mouse anti-Human Monoclonal (8D2B8) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

CD59 Antibody (clone MEM-43, Preservative Free) LS-C43261

Antibody:

CD59 Mouse anti-Human Monoclonal (Preservative Free) (MEM-43) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated, Preservative Free

Price:

1 mg/$1,091

Select

CD59 Antibody (Biotin) LS-C35698

Antibody:

CD59 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

Flo

Format:

Biotin Conjugated

Price:

100 µg/$626

Select

CD59 Antibody (aa26-98) LS-C296093

Antibody:

CD59 Rabbit anti-Pig Polyclonal (aa26-98) Antibody

Reactivity:

Pig

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$322; 200 µl/$370; 500 µl/$529; 1 ml/$614; 2 ml/$846; 5 ml/$1,393

Select

CD59 Antibody (clone MACIF/2867R, Azide-free, Carrier-free) LS-C751477

Antibody:

CD59 Rabbit anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (MACIF/2867R) Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated, Azide-free, Carrier-free

Price:

100 µg/$574

Select

CD59 Antibody (clone TH9) LS-C209613

(4.0) Rating

(1) Publication(s)

Antibody:

CD59 Mouse anti-Rat Monoclonal (TH9) Antibody

Reactivity:

Rat

Applications:

Flo, Func, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

100 µg/$652

Select

Human CD59 (Sandwich ELISA) ELISA Kit - LS-F11090

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Human CD59 (Sandwich ELISA) ELISA Kit - LS-F6544

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

12.5 - 800 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$798

Select

IHC-plus™ CD59 Antibody (clone MEM-43) LS-B2106

(4.0) Rating

Antibody:

CD59 Mouse anti-Human Monoclonal (MEM-43) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

CD59 Antibody (clone 7A6) LS-C210252

(4.1) Rating

(2) Publication(s)

Antibody:

CD59 Mouse anti-Mouse Monoclonal (7A6) Antibody

Reactivity:

Mouse

Applications:

Flo, Func, IF, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

100 µg/$516

Select

CD59 Antibody (clone 7A6, FITC) LS-C210253

Antibody:

CD59 Mouse anti-Mouse Monoclonal (FITC) (7A6) Antibody

Reactivity:

Mouse

Applications:

Flo, Func, IF, IHC, IHC-Fr, WB

Format:

FITC Conjugated

Price:

100 µg/$571

Select

CD59 Antibody (Biotin) LS-C317300

Antibody:

CD59 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

Human CD59 Protein (Recombinant 6His, N-terminus) (aa26-102) - LS-G22850

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

11 kD

Price:

1 mg/$1,607; 100 µg/$469; 20 µg/$349

Select

CD59 Antibody (aa26-102, Biotin) LS-C298909

Antibody:

CD59 Rabbit anti-Human Polyclonal (aa26-102) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279

Select

IHC-plus™ CD59 Antibody (FITC) LS-B6568

(4.0) Rating

Antibody:

CD59 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P

Format:

FITC Conjugated

Price:

60 Tests/$545

Select

CD59 Antibody LS-C403048

Antibody:

CD59 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

CD59 Antibody (clone 031, Preservative Free) LS-C818899

Antibody:

CD59 Rabbit anti-Human Monoclonal (Preservative Free) (031) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

20 µl/$271; 100 µl/$412

Select

CD59 Antibody (clone 015, Preservative Free) LS-C820634

Antibody:

CD59 Rabbit anti-Human Monoclonal (Preservative Free) (015) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

20 µl/$271; 100 µl/$412

Select

CD59 Antibody (clone YTH53.1) LS-C45292

Antibody:

CD59 Rat anti-Human Monoclonal (YTH53.1) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

0.2 mg/$471

Select

CD59 Antibody (clone 001, APC) LS-C819440

Antibody:

CD59 Rabbit anti-Rat Monoclonal (APC) (001) Antibody

Reactivity:

Rat

Applications:

Flo

Format:

APC Conjugated

Price:

25 Tests/$233; 100 Tests/$263

Select

CD59 Antibody (clone 014, PE) LS-C819443

Antibody:

CD59 Rabbit anti-Rat Monoclonal (PE) (014) Antibody

Reactivity:

Rat

Applications:

Flo

Format:

PE Conjugated

Price:

25 Tests/$233; 100 Tests/$263

Viewing 1-25 of 243 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.