Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
CD55 antibody was raised against human fibroblast cell line.
Recognizes the CD55 antigen a 70kD glycoprotein also known as Decay Accelerating Factor (DAF). The antigen is present on erythrocytes and other circulating blood cells and also on cells in non-hemopoietic tissue particularly epithelium and endothelium. It is found specifically at the placental fetal-maternal interface.
Immunoprecipitation studies of the CD55 antigen. Blocking studies in CD55 expression. Flow Cytometry.
10 mM Sodium Azide, 1 mg/ml BSA
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.