Human CD47

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1,k Monoclonal

B6H12.2

Unconjugated

Protein G purified

Azide-free, BSA-free. Also available Unmodified.

Intact CD47 purified from placenta.

Human CD47

• IHC
• IHC - Paraffin (0.5 - 1 µg/ml)
• Immunofluorescence (1 - 2 µg/ml)
• Western blot
• Flow Cytometry (0.5 - 1 µg/10E6 cells)
• Blocking
• Functional Assay

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody reacts with the Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. Functional Activity/blocking: Order BSA/Azide-free format

1X PBS

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q08722 NCBI: NM_001777 NP_001768.1