Target
Human CD46
Synonyms
CD46 | AHUS2 | CD46 antigen | MCP | Measles virus receptor | TLX | MIC10 | TRA2.10 | Membrane cofactor protein
Reactivity
Human, Bovine
(tested or 100% immunogen sequence identity)
Immunogen
HPB-ALL human T cell line
Specificity
The antibody MEM-258 recognizes an epitope on SCR4 (the membrane-proximal SCR) domain of CD46 (Membrane cofactor protein). CD46 is 56-66 kDa dimeric transmembrane protein expressed on T and B lymphocytes, platelets, monocytes, granulocytes, endothelial cells, epithelial cells and fibroblast; it is negative on erythrocytes.