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Catalog Number Size Price
LS-C388207-100 100 µg $506 
CD40L Antibody - IHC-P: CD40L antibody testing of rat intestine tissue
CD40L Antibody - Western blot testing of CD40L antibody and Lane 1: MCF-7; 2: HeLa; 3: Jurkat; 4: HMY2; 5: COLO320; Predicted size: 29KD; Observed size: 29KD
CD40L Antibody - IHC-P: CD40L antibody testing of rat intestine tissue
CD40L Antibody - Western blot testing of CD40L antibody and Lane 1: MCF-7; 2: HeLa; 3: Jurkat; 4: HMY2; 5: COLO320; Predicted size: 29KD; Observed size: 29KD
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Polyclonal Rabbit anti‑Human CD40L Antibody (aa47‑65, IHC, WB) LS‑C388207

Polyclonal Rabbit anti‑Human CD40L Antibody (aa47‑65, IHC, WB) LS‑C388207

Antibody:
CD40L Rabbit anti-Human Polyclonal (aa47-65) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Bat, Bovine, Horse, Pig, Rabbit, Sheep
Format:
Unconjugated, Unmodified
Price
Catalog Number
$506
LS-C388207-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
CD40L Rabbit anti-Human Polyclonal (aa47-65) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Bat, Bovine, Horse, Pig, Rabbit, Sheep
Format:
Unconjugated, Unmodified

Specifications

Description
CD40L antibody LS-C388207 is an unconjugated rabbit polyclonal antibody to CD40L (aa47-65) from human. It is reactive with human, bat, bovine and other species. Validated for IHC and WB.
Target
Human CD40L
Synonyms
CD40LG | CD154 | CD154 antigen | CD40-L | CD40 ligand | CD40L | gp39 | HIGM1 | IGM | IMD3 | T-BAM | TNFSF5 | CD40 antigen ligand | CD54 | HCD40L | T-B cell-activating molecule | T-cell antigen Gp39 | TNF-related activation protein
Host
Rabbit
Reactivity
Human, Bat, Bovine, Horse, Pig, Rabbit, Sheep (tested or 100% immunogen sequence identity)
Predicted
Dog (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from the N-Terminus of human CD40L (HRRLDKIEDERNLHEDFVF, aa47-65 of UniProt P29965). Percent identity by BLAST analysis: Human, Sheep, Bovine, Bat, Elephant, Rabbit, Horse, Pig (100%); Ferret, Cat, Dog (95%); Guinea pig (89%); Mouse (84%); Rat (79%).
Epitope
aa47-65
Specificity
Human CD40L
Applications
  • IHC
  • IHC - Paraffin (0.5 - 1 µg/ml)
  • Western blot (0.5 - 1 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
CD40 ligand (CD40L) is a type II membrane protein of 261 amino acids on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumour necrosis factor-alpha and -beta, and has important functions in B-cell activation and differentiation. Human CD40L with 5 exons, is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1, and can be detected on T cells but is absent from B cells and monocytes. Since CD40L is expressed on platelets and released from them on activation, its predictive value as a marker for clinical outcome and the therapeutic effect of inhibition of glycoprotein IIb /IIIa receptor in patients with acute coronary syndromes was investigated. The soluble CD40L may be involved in the process of restenosis and that it exerts its effect by triggering a complex group of inflammatory reactions on endothelial and mononuclear cells. CD40L plays a central role in the pathophysiology of acute coronary syndromes, and has a role in the pathogenesis of coronary artery lesions.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
After reconstitution, may be stored at 4°C for 1 month. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CD40L
P29965 NM_000074 NP_000065.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/27/2021