Mouse CD3E

Rabbit

Mouse, Human, Orangutan, Monkey, Rat (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Protein A purified

Unmodified. Also available Azide-free, BSA-free.

Amino acids ERPPPVPNPDYEP (156-168). Percent identity by BLAST analysis: Human, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Rabbit, Pig (100%); Chimpanzee, Gorilla, Ferret, Cat, Chicken, Dog (92%).

Mouse CD3e.

• Western blot (0.5 - 1 µg/ml)

This antibody recognizes the epsilon-chain of CD3 (CD3e), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the Tcell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the Tcell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the Tcell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the Tcell surface. CD3 antigen is a highly specific marker for Tcells, and is present in majority of Tcell neoplasms.

1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

NCBI: NM_000733 NP_000724.1