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Catalog Number Size Price
LS-C743961-1 1 ml (40 µg/ml) $543 
Antibody

Monoclonal Mouse anti‑Human CD34 Antibody (IHC) LS‑C743961

Monoclonal Mouse anti‑Human CD34 Antibody (IHC) LS‑C743961

Antibody:
CD34 Mouse anti-Human Monoclonal Antibody
Application:
IHC-P
Reactivity:
Human, Rhesus monkey
Format:
Unconjugated, Unmodified
Price
Catalog Number
$543
LS-C743961-1
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
CD34 Mouse anti-Human Monoclonal Antibody
Application:
IHC-P
Reactivity:
Human, Rhesus monkey
Format:
Unconjugated, Unmodified

Specifications

Description
CD34 antibody LS-C743961 is an unconjugated mouse monoclonal antibody to CD34 from human. It is reactive with human and rhesus monkey. Validated for IHC.
Target
Human CD34
Synonyms
CD34 | CD34 molecule | CD34 antigen | HPCA1
Host
Mouse
Reactivity
Human, Rhesus monkey (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Conjugations
Unconjugated
Modifications
Unmodified
Immunogen
Purified human endothelial vesicles
Applications
  • IHC - Paraffin (1:10 - 1:20)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
No protease pre-treatment! Pre-treatment with antigen retrieval at 90-100°C may be helpful. The antibody clone QBEND/1 reacts with an epitope on endothelial cells and haematopoietic progenitor cells, which is not sensitive to neuraminidase but to chymopapain and glycoprotease (CD34 class II antibodies). It may be used for the detection of endothelial cells and haematopoietic progenitor cells in tissues, cell smears and cell cultures. The CD34 molecule is a glycoprotein (110 kDa), which is expressed as well by endothelial cells as by haematopoietic precursor cells (BFU-E, CFU-GM, CFU-Meg, CFU-Eo, CFU-osteoclasts and CFU-blasts) in human bone marrow. CD34 is the earliest marker of colony building cells in bone marrow. The molecule is heavily glycosylated in the N-terminal extracellular region and therefore sensitive to neuraminidase (target of CD34 class I antibodies). This region is followed by a globular Cys-rich domain. The cytoplasmic portion of the molecule contains sites for proteinkinase C and tyrosine phosphorylation. Human CD34 antigen (Epitope neuraminidase resistant , glycoprotease- and chymopapain-sensitive).
Presentation
PBS, pH 7.3, 0.09% Sodium Azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CD34
P28906 NM_001773 NP_001764.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 1/20/2022