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Catalog Number Size Price
LS-C357759-20 20 µg (0.2 mg/ml) $347 
LS-C357759-100 100 µg (0.2 mg/ml) $522 
Antibody

Monoclonal Mouse anti‑Human CD33 Antibody (clone WM53, IF) LS‑C357759

Monoclonal Mouse anti‑Human CD33 Antibody (clone WM53, IF) LS‑C357759

Antibody:
CD33 Mouse anti-Human Monoclonal (WM53) Antibody
Application:
IF, Flo, Func
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$347
LS-C357759-20
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
CD33 Mouse anti-Human Monoclonal (WM53) Antibody
Application:
IF, Flo, Func
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
CD33 antibody LS-C357759 is an unconjugated mouse monoclonal antibody to human CD33. Validated for Flow, Func and IF.
Target
Human CD33
Synonyms
CD33 | CD33 antigen | CD33 molecule | gp67 | SIGLEC-3 | p67 | CD33 antigen (gp67) | SIGLEC3
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Clone
WM53
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified. Also available Azide-free, BSA-free.
Immunogen
Human AML cells were used as the immunogen for this CD33 antibody.
Specificity
Human CD33
Applications
  • Immunofluorescence (0.5 - 1 µg/ml)
  • Flow Cytometry (0.5 - 1 µg/10E6 cells)
  • Functional Assay
Usage
This antibody recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV. WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies. these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells. ELISA: Order BSA-free antibody format for coating.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CD33
P20138 NM_001772 NP_001763.3

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 12/4/2021