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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD30 Antibody (clone CD30/412) LS‑C357756
CD30 antibody LS-C357756 is an unconjugated mouse monoclonal antibody to human CD30. Validated for ELISA, Flow, IF and IHC.
Catalog
Size
Price
LS-C357756-20
20 µg
$255
LS-C357756-100
100 µg (0.2 mg/ml)
$395

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Product Description

CD30 antibody LS-C357756 is an unconjugated mouse monoclonal antibody to human CD30. Validated for ELISA, Flow, IF and IHC.
About CD30
CD30 is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. P28908 NM_001243 NP_001234.3

TNFRSF8 Antibody, CD30L receptor Antibody, CD30 Antibody, Cytokine receptor CD30 Antibody, D1S166E Antibody, Ki-1 Antibody, Ki-1 antigen Antibody, CD30 antigen Antibody


Specifications

Target
Human CD30
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal [CD30/412]
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified. Also available Ready-to-Use, Azide-free.
Applications
  • IHC
  • IHC - Paraffin (0.5 - 1 µg/ml)
  • Immunofluorescence (1 - 2 µg/ml)
  • Flow Cytometry (0.5 - 1 µg/10E6 cells)
  • ELISA
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CD30 antibody was raised against human CD30 recombinant protein.
Specificity
Human CD30
Usage
The antibody recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin's disease, CD30 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This antibody distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the CD30 positive lymphomas lack the leukocyte common antigen (CD45). ELISA: Order BSA-free format for coating.
Presentation
PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only.

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Images

Immunohistochemistry

CD30 antibody CD30/412 immunohistochemistry 20X-2.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CD30 antibody CD30/412 immunohistochemistry 20X-2. This image was taken for the unmodified form of this product. Other forms have not been tested.

Immunohistochemistry

CD30 antibody CD30/412 immunohistochemistry 20X-1.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CD30 antibody CD30/412 immunohistochemistry 20X-1. This image was taken for the unmodified form of this product. Other forms have not been tested.

Immunohistochemistry

CD30 antibody CD30/412 immunohistochemistry 20X-2.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CD30 antibody CD30/412 immunohistochemistry 20X-2. This image was taken for the unmodified form of this product. Other forms have not been tested.

Immunohistochemistry

CD30 antibody CD30/412 immunohistochemistry 20X-1.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CD30 antibody CD30/412 immunohistochemistry 20X-1. This image was taken for the unmodified form of this product. Other forms have not been tested.

Immunohistochemistry

CD30 antibody CD30/412 immunohistochemistry 20X-2.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CD30 antibody CD30/412 immunohistochemistry 20X-2. This image was taken for the unmodified form of this product. Other forms have not been tested.

Immunohistochemistry

CD30 antibody CD30/412 immunohistochemistry 20X-1.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CD30 antibody CD30/412 immunohistochemistry 20X-1. This image was taken for the unmodified form of this product. Other forms have not been tested.

Immunohistochemistry

CD30 antibody CD30/412 immunohistochemistry 20X-2.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CD30 antibody CD30/412 immunohistochemistry 20X-2. This image was taken for the unmodified form of this product. Other forms have not been tested.

Immunohistochemistry

CD30 antibody CD30/412 immunohistochemistry 20X-1.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CD30 antibody CD30/412 immunohistochemistry 20X-1. This image was taken for the unmodified form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 9/20/2018

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