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| Catalog Number | Size | Price |
|---|---|---|
| LS-C188547-0.25 | 0.25 mg (0.5 mg/ml) | $454 |
Monoclonal Rat anti‑Mouse CD105 Antibody (clone MJ7/18, IHC, WB) LS‑C188547
Monoclonal Rat anti‑Mouse CD105 Antibody (clone MJ7/18, IHC, WB) LS‑C188547
Antibody:
CD105 Rat anti-Mouse Monoclonal (MJ7/18) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB, IP, Flo
Reactivity:
Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
CD105 Rat anti-Mouse Monoclonal (MJ7/18) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB, IP, Flo
Reactivity:
Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
CD105 antibody LS-C188547 is an unconjugated rat monoclonal antibody to mouse CD105. Validated for Flow, IHC, IP and WB.
Target
Mouse CD105
Synonyms
ENG | CD105 | CD105 antigen | END | HHT1 | ORW | ORW1 | Osler-Rendu-Weber syndrome 1 | Endoglin
Host
Rat
Reactivity
Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG2a
Monoclonal
Clone
MJ7/18
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Inflamed mouse skin.
Specificity
Recognizes mouse CD105, also known as Endoglin, a cell surface glycoprotein member of the TGF beta receptor complex. CD105 is a homodimer that forms a heteromeric complex with TGF beta receptors I and/or II. The complex binds TGF beta 1 and 3 efficiently, and TGF beta 2 less efficiently. It may also play a role in the binding of endothelial cells to integrins and cytoskeletal organisation. It is involved in cardiovascular development. CD105 is expressed on endothelial cells in all tissues except bone marrow and in also found in stromal cells within the connective tissue of the intestine, stomach and heart. It may be a useful marker for proliferating endothelium in tumors.
Applications
- IHC
- IHC - Paraffin
- IHC - Frozen
- Western blot
- Immunoprecipitation
- Flow Cytometry (1:10 - 1:20)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CD105
Publications (0)
Customer Reviews (0)
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Species:
Human, Monkey, Mouse, Rat, Dog
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Porcine
Applications:
IHC - Frozen, ICC, Western blot, Flow Cytometry
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human, Mouse
Applications:
IHC, Western blot, Flow Cytometry, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/24/2024
Date Requested: 4/24/2024
