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CCND2 / Cyclin D2
cyclin D2
Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
| Gene Name: | cyclin D2 |
| Synonyms: | CCND2, KIAK0002, G1/S-specific cyclin D2, G1/S-specific cyclin-D2, Cyclin D2 |
| Target Sequences: | NM_001759 NP_001750.1 P30279 |
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CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
CCND2 / Cyclin D2 Mouse anti-Human Monoclonal (DCS3.1) Antibody
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
100 µg/$466
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal (220-300 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal (aa240-289) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$341
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal (aa1-289) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal (220-300 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
CCND2 / Cyclin D2 Mouse anti-Human Monoclonal (DCS-5) Antibody
Mouse
ICC, IP, WB
Unconjugated
100 µg/$380
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µg/$442
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
50 µl/$317; 100 µl/$375; 200 µl/$473
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal (pThr280) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CCND2 / Cyclin D2 Mouse anti-Human Monoclonal Antibody
Mouse, Human
ICC, WB
Unconjugated
100 µg/$564
CCND2 / Cyclin D2 Mouse anti-Human Monoclonal (CY-D2) Antibody
Mouse, Human
ICC, WB
Unconjugated
100 µg/$380
CCND2 / Cyclin D2 Mouse anti-Human Monoclonal (Sepharose) (CY-D2) Antibody
Mouse, Human
IP
Sepharose Conjugated
100 µg/$399
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CCND2 / Cyclin D2 Mouse anti-Human Monoclonal (3B10) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
CCND2 / Cyclin D2 Rabbit anti-Human Polyclonal (RPE) Antibody
Human
IHC, WB
RPE Conjugated
100 µg/$477
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