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Catalog Number Size Price
LS-C357829-100 100 Tests (0.1 mg/ml) $522 
CCND1 / Cyclin D1 Antibody - Cyclin D1 antibody FACS MCF-7
CCND1 / Cyclin D1 Antibody - Cyclin D1 antibody FACS Jurkat
CCND1 / Cyclin D1 Antibody - Cyclin D1 antibody FACS MCF-7
CCND1 / Cyclin D1 Antibody - Cyclin D1 antibody FACS Jurkat
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Monoclonal Mouse anti‑Human CCND1 / Cyclin D1 Antibody (clone DCS‑6, PE, IF) LS‑C357829

Monoclonal Mouse anti‑Human CCND1 / Cyclin D1 Antibody (clone DCS‑6, PE, IF) LS‑C357829

Antibody:
CCND1 / Cyclin D1 Mouse anti-Human Monoclonal (PE) (DCS-6) Antibody
Application:
IF, Flo
Reactivity:
Human, Monkey, Mouse, Rat
Format:
Phycoerythrin, Unmodified
Price
Catalog Number
$522
LS-C357829-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
CCND1 / Cyclin D1 Mouse anti-Human Monoclonal (PE) (DCS-6) Antibody
Application:
IF, Flo
Reactivity:
Human, Monkey, Mouse, Rat
Format:
Phycoerythrin, Unmodified

Specifications

Description
Cyclin D1 antibody LS-C357829 is a PE-conjugated mouse monoclonal antibody to Cyclin D1 (CCND1) from human. It is reactive with human, mouse, rat and other species. Validated for Flow and IF.
Target
Human CCND1 / Cyclin D1
Synonyms
CCND1 | B-cell lymphoma 1 protein | BCL-1 oncogene | B-cell CLL/lymphoma 1 | BCL-1 | Cyclin D1 | G1/S-specific cyclin-D1 | U21B31 | PRAD1 | BCL1 | D11S287E | PRAD1 oncogene
Host
Mouse
Reactivity
Human, Monkey, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal
Clone
DCS-6
Conjugations
Phycoerythrin
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Human recombinant full length cyclin D1 protein
Specificity
Human CCND1 / Cyclin D1
Applications
  • Immunofluorescence (1:50 - 1:100)
  • Flow Cytometry
Usage
This antibody recognizes a protein of 36kDa, identified as Cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11. 14)(q13. q32) translocation resulting in over-expression. The antibody is useful in identifying mantle cell lymphomas (Cyclin D1 positive) from CLL/SLL and follicular lymphomas (Cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Presentation
0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C. Do not freeze.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CCND1 / Cyclin D1
P24385 NM_053056 NP_444284.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 12/4/2021