Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
| Catalog Number | Size | Price |
|---|---|---|
| LS-C357829-100 | 100 Tests (0.1 mg/ml) | $574 |
1 of 2
2 of 2
Monoclonal Mouse anti‑Human CCND1 / Cyclin D1 Antibody (clone DCS‑6, PE, IF) LS‑C357829
Monoclonal Mouse anti‑Human CCND1 / Cyclin D1 Antibody (clone DCS‑6, PE, IF) LS‑C357829
Antibody:
CCND1 / Cyclin D1 Mouse anti-Human Monoclonal (PE) (DCS-6) Antibody
Application:
IF, Flo
Reactivity:
Human, Monkey, Mouse, Rat
Format:
Phycoerythrin, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
CCND1 / Cyclin D1 Mouse anti-Human Monoclonal (PE) (DCS-6) Antibody
Application:
IF, Flo
Reactivity:
Human, Monkey, Mouse, Rat
Format:
Phycoerythrin, Unmodified
Specifications
Description
Cyclin D1 antibody LS-C357829 is a PE-conjugated mouse monoclonal antibody to Cyclin D1 (CCND1) from human. It is reactive with human, mouse, rat and other species. Validated for Flow and IF.
Target
Human CCND1 / Cyclin D1
Synonyms
CCND1 | B-cell lymphoma 1 protein | BCL-1 oncogene | B-cell CLL/lymphoma 1 | BCL-1 | Cyclin D1 | G1/S-specific cyclin-D1 | U21B31 | PRAD1 | BCL1 | D11S287E | PRAD1 oncogene
Host
Mouse
Reactivity
Human, Monkey, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG2a,k
Monoclonal
Clone
DCS-6
Conjugations
Phycoerythrin
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Human recombinant full length cyclin D1 protein
Specificity
Human CCND1 / Cyclin D1
Applications
- Immunofluorescence (1:50 - 1:100)
- Flow Cytometry
Usage
This antibody recognizes a protein of 36kDa, identified as Cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11. 14)(q13. q32) translocation resulting in over-expression. The antibody is useful in identifying mantle cell lymphomas (Cyclin D1 positive) from CLL/SLL and follicular lymphomas (Cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Presentation
0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C. Do not freeze.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CCND1 / Cyclin D1
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Mouse, Rat
Applications:
Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot
Species:
Human
Applications:
Western blot, Immunoprecipitation, ELISA
Species:
Human, Mouse, Rat
Applications:
Immunoprecipitation
Species:
Human, Monkey, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/24/2024
Date Requested: 4/24/2024
