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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCL14 Antibody (aa20‑93, Cy3) LS‑C700040
CCL14 antibody LS-C700040 is a Cy3-conjugated rabbit polyclonal antibody to human CCL14. Validated for IHC and WB.
Catalog
Size
Price
LS-C700040-20
20 µl
$245
LS-C700040-100
100 µl
$345
LS-C700040-200
200 µl
$425
LS-C700040-1
1 ml
$995
LS-C700040-10
10 ml
$3,975

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Product Description

CCL14 Antibody (aa20-93, Cy3) for IHC, WB/Western LS-C700040

Specifications

Target
Human CCL14
Synonyms
CCL14, CC-3, C-C motif chemokine 14, Chemokine cc3, Chemokine CC-1/CC-3, Chemokine cc1, Chemokine CC-3, HCC-1(1-74), Hcc3, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, Small-inducible cytokine A14, SY14, CC-1, CKB1, HCC1, Hemofiltrate CC chemokine 1, NCC2, New CC chemokine 2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Cy3. Also available Unconjugated or conjugated with FITC, Biotin, FITC, HRP, PE, APC, Cy7, APC.
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CCL14 antibody was raised against recombinant CCL14 (Thr20-Asn93) expressed in E. coli.
Epitope
aa20-93
Specificity
The antibody is a rabbit polyclonal antibody raised against CCL14. It has been selected for its ability to recognize CCL14 in immunohistochemical staining and western blotting.
Presentation
PBS, pH 7.4, 0.02% Sodium Azide, 50% Glycerol
Storage
Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.
Restrictions
For research use only.
About CCL14
Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca2+ changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. Q16627 NM_004166 NP_004157.1


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Images

Western blot

Western blot of recombinant Hcc1 / CCL14.
Western blot of recombinant Hcc1 / CCL14.

Western blot

Western blot of recombinant Hcc1 / CCL14.
Western blot of recombinant Hcc1 / CCL14.

Western blot

Western blot of recombinant Hcc1 / CCL14.
Western blot of recombinant Hcc1 / CCL14.

Western blot

Western blot of recombinant Hcc1 / CCL14.
Western blot of recombinant Hcc1 / CCL14.

Requested From: United States
Date Requested: 10/21/2018

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