Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CAV2, Caveolin 2 isoform a and b, Caveolin-2, CAV, Caveolae protein, 20-kD, Caveolin 2
(tested or 100% immunogen sequence identity)
Human synthetic peptide corresponding to amino acids 18-31 of caveolin-2 phosphorylated on serine 23.
This immunoaffinity purified antibody Detects a ~21kD band corresponding to Caveolin-2 in samples of human. This antibody is specific for the non-phosphorylated Caveolin-2 and does not detect phosphorylated Caveolin-2. The affinity purified product has been cross adsorbed against the phosphorylated peptide to remove antibodies that may detect the phosphorylated form of the protein.
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway.