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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CAV2 / Caveolin 2 Antibody LS‑C498386
Caveolin 2 antibody LS-C498386 is an unconjugated rabbit polyclonal antibody to human Caveolin 2 (CAV2). Validated for ELISA, IF and IHC.
Catalog
Size
Price
LS-C498386-50
50 µg
$285
LS-C498386-100
100 µg
$385

Popular CAV2 / Caveolin 2 Products

Immunohistochemistry of paraffin-embedded human uterus using CAV2 antibodyat dilution of 1:100 (40x lens).
Species: Human
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation
Formalin-fixed and paraffin-embedded human skeletal muscle reacted with CAV2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
IHC of paraffin-embedded FaDu xenograft using Caveolin 2 antibody at 1:500 dilution.
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Dog
Applications: IHC, IHC - Paraffin, Western blot

Product Description

CAV2 / Caveolin 2 Antibody for IHC, IF/Immunofluorescence, ELISA LS-C498386

Specifications

Target
Human CAV2 / Caveolin 2
Synonyms
CAV2, Caveolin 2 isoform a and b, Caveolin-2, CAV, Caveolae protein, 20-kD, Caveolin 2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with FITC, Biotin, HRP.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • Immunofluorescence
  • ELISA
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant Human Caveolin-2 protein (3-64AA)
Specificity
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only.
About CAV2 / Caveolin 2
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. P51636 NM_001233 NP_001224.1


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Images

Immunohistochemistry

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA004572LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA004572LA01HU at dilution of 1:100

Immunohistochemistry

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA004572LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA004572LA01HU at dilution of 1:100

Immunofluorescence

Immunofluorescent analysis of A549 cells using CSB-PA004572LA01HU at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunofluorescent analysis of A549 cells using CSB-PA004572LA01HU at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunohistochemistry

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA004572LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA004572LA01HU at dilution of 1:100

Immunohistochemistry

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA004572LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA004572LA01HU at dilution of 1:100

Immunofluorescence

Immunofluorescent analysis of A549 cells using CSB-PA004572LA01HU at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunofluorescent analysis of A549 cells using CSB-PA004572LA01HU at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunohistochemistry

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA004572LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA004572LA01HU at dilution of 1:100

Immunohistochemistry

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA004572LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA004572LA01HU at dilution of 1:100

Immunofluorescence

Immunofluorescent analysis of A549 cells using CSB-PA004572LA01HU at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunofluorescent analysis of A549 cells using CSB-PA004572LA01HU at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunohistochemistry

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA004572LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA004572LA01HU at dilution of 1:100

Immunohistochemistry

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA004572LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA004572LA01HU at dilution of 1:100

Immunofluorescence

Immunofluorescent analysis of A549 cells using CSB-PA004572LA01HU at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunofluorescent analysis of A549 cells using CSB-PA004572LA01HU at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Requested From: United States
Date Requested: 10/20/2018

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