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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CAV2 / Caveolin 2 Antibody (aa1‑17) LS‑C312696
Note: This antibody replaces LS-C388142
Caveolin 2 antibody LS-C312696 is an unconjugated rabbit polyclonal antibody to Caveolin 2 (CAV2) from human, bovine, guinea pig and other species. Validated for IHC and WB.
Catalog
Size
Price
LS-C312696-100
100 µg (0.5 mg/ml)
$355

Popular CAV2 / Caveolin 2 Products

Immunohistochemistry of paraffin-embedded human uterus using CAV2 antibodyat dilution of 1:100 (40x lens).
Species: Human
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation
Formalin-fixed and paraffin-embedded human skeletal muscle reacted with CAV2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
IHC of paraffin-embedded FaDu xenograft using Caveolin 2 antibody at 1:500 dilution.
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Dog
Applications: IHC, IHC - Paraffin, Western blot
Immunohistochemistry of paraffin-embedded human lung tissue using CAV2 Antibody at dilution of 1:100
Species: Human
Applications: IHC, Immunofluorescence, ELISA

Product Description

Caveolin 2 antibody LS-C312696 is an unconjugated rabbit polyclonal antibody to Caveolin 2 (CAV2) from human, bovine, guinea pig and other species. Validated for IHC and WB.

Specifications

Target
Human CAV2 / Caveolin 2
Synonyms
CAV2, Caveolin 2 isoform a and b, Caveolin-2, CAV, Caveolae protein, 20-kD, Caveolin 2
Host
Rabbit
Reactivity
Human, Monkey, Bovine, Guinea pig, Pig, Rabbit, Sheep (tested or 100% immunogen sequence identity)
Predicted
Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunogen affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Caveolin-2(1-17aa MGLETEKADVQLFMDDD), different from the related rat and mouse sequences by one amino acid.
Epitope
aa1-17
Specificity
Expressed in endothelial cells, smooth muscle cells, skeletal myoblasts and fibroblasts. .
Presentation
Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 ug antibody.
Reconstitution
200 µl Distilled water
Storage
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
Restrictions
For research use only.
About CAV2 / Caveolin 2
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. P51636 NM_001233 NP_001224.1


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Images

Immunohistochemistry

CAV2 / Caveolin 2 antibody. IHC(P): Rat Cardiac Muscle Tissue.
CAV2 / Caveolin 2 antibody. IHC(P): Rat Cardiac Muscle Tissue.

Immunohistochemistry

CAV2 / Caveolin 2 antibody. IHC(P): Human Lung Cancer Tissue.
CAV2 / Caveolin 2 antibody. IHC(P): Human Lung Cancer Tissue.

Western blot

WB of CAV2 / Caveolin 2 antibody. All lanes: Anti-CAV2 at 0.5ug/ml. Lane 1: Rat Heart Tissue Lysate at 40ug. Lane 2: Rat lung Tissue Lysate at 40ug. Lane 3: HELA Whole Cell Lysate at 40ug. Lane 4: A431 Whole Cell Lysate at 40ug. Predicted bind size: 17KD. Observed bind size: 22KD.
WB of CAV2 / Caveolin 2 antibody. All lanes: Anti-CAV2 at 0.5ug/ml. Lane 1: Rat Heart Tissue Lysate at 40ug. Lane 2: Rat lung Tissue Lysate at 40ug. Lane 3: HELA Whole Cell Lysate at 40ug. Lane 4: A431 Whole Cell Lysate at 40ug. Predicted bind size: 17KD. Observed bind size: 22KD.

Immunohistochemistry

CAV2 / Caveolin 2 antibody. IHC(P): Rat Cardiac Muscle Tissue.
CAV2 / Caveolin 2 antibody. IHC(P): Rat Cardiac Muscle Tissue.

Immunohistochemistry

CAV2 / Caveolin 2 antibody. IHC(P): Human Lung Cancer Tissue.
CAV2 / Caveolin 2 antibody. IHC(P): Human Lung Cancer Tissue.

Western blot

WB of CAV2 / Caveolin 2 antibody. All lanes: Anti-CAV2 at 0.5ug/ml. Lane 1: Rat Heart Tissue Lysate at 40ug. Lane 2: Rat lung Tissue Lysate at 40ug. Lane 3: HELA Whole Cell Lysate at 40ug. Lane 4: A431 Whole Cell Lysate at 40ug. Predicted bind size: 17KD. Observed bind size: 22KD.
WB of CAV2 / Caveolin 2 antibody. All lanes: Anti-CAV2 at 0.5ug/ml. Lane 1: Rat Heart Tissue Lysate at 40ug. Lane 2: Rat lung Tissue Lysate at 40ug. Lane 3: HELA Whole Cell Lysate at 40ug. Lane 4: A431 Whole Cell Lysate at 40ug. Predicted bind size: 17KD. Observed bind size: 22KD.

Immunohistochemistry

CAV2 / Caveolin 2 antibody. IHC(P): Rat Cardiac Muscle Tissue.
CAV2 / Caveolin 2 antibody. IHC(P): Rat Cardiac Muscle Tissue.

Immunohistochemistry

CAV2 / Caveolin 2 antibody. IHC(P): Human Lung Cancer Tissue.
CAV2 / Caveolin 2 antibody. IHC(P): Human Lung Cancer Tissue.

Western blot

WB of CAV2 / Caveolin 2 antibody. All lanes: Anti-CAV2 at 0.5ug/ml. Lane 1: Rat Heart Tissue Lysate at 40ug. Lane 2: Rat lung Tissue Lysate at 40ug. Lane 3: HELA Whole Cell Lysate at 40ug. Lane 4: A431 Whole Cell Lysate at 40ug. Predicted bind size: 17KD. Observed bind size: 22KD.
WB of CAV2 / Caveolin 2 antibody. All lanes: Anti-CAV2 at 0.5ug/ml. Lane 1: Rat Heart Tissue Lysate at 40ug. Lane 2: Rat lung Tissue Lysate at 40ug. Lane 3: HELA Whole Cell Lysate at 40ug. Lane 4: A431 Whole Cell Lysate at 40ug. Predicted bind size: 17KD. Observed bind size: 22KD.

Immunohistochemistry

CAV2 / Caveolin 2 antibody. IHC(P): Rat Cardiac Muscle Tissue.
CAV2 / Caveolin 2 antibody. IHC(P): Rat Cardiac Muscle Tissue.

Immunohistochemistry

CAV2 / Caveolin 2 antibody. IHC(P): Human Lung Cancer Tissue.
CAV2 / Caveolin 2 antibody. IHC(P): Human Lung Cancer Tissue.

Western blot

WB of CAV2 / Caveolin 2 antibody. All lanes: Anti-CAV2 at 0.5ug/ml. Lane 1: Rat Heart Tissue Lysate at 40ug. Lane 2: Rat lung Tissue Lysate at 40ug. Lane 3: HELA Whole Cell Lysate at 40ug. Lane 4: A431 Whole Cell Lysate at 40ug. Predicted bind size: 17KD. Observed bind size: 22KD.
WB of CAV2 / Caveolin 2 antibody. All lanes: Anti-CAV2 at 0.5ug/ml. Lane 1: Rat Heart Tissue Lysate at 40ug. Lane 2: Rat lung Tissue Lysate at 40ug. Lane 3: HELA Whole Cell Lysate at 40ug. Lane 4: A431 Whole Cell Lysate at 40ug. Predicted bind size: 17KD. Observed bind size: 22KD.

Requested From: United States
Date Requested: 11/12/2018

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