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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASP1 / Caspase 1 Antibody IHC‑plus™ LS‑B3394
Note: This antibody replaces LS-C50656
Caspase 1 antibody LS-B3394 is an unconjugated rabbit polyclonal antibody to human Caspase 1 (CASP1). Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B3394-250
250 µl
$425

Popular CASP1 / Caspase 1 Products

Antibody
Species: Mouse
Applications: Western blot, Flow Cytometry, ELISA
Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B112 concentration 20 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse, Rat
Applications: ICC, Western blot, Immunoprecipitation
Anti-Caspase 1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3199 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

Caspase 1 antibody LS-B3394 is an unconjugated rabbit polyclonal antibody to human Caspase 1 (CASP1). Validated for IHC. Tested on 20 paraffin-embedded human tissues.
About CASP1 / Caspase 1
CASP1 / Caspase 1 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. P29466 NM_001223 NP_001214.1

CASP1 Antibody, Caspase-1 Antibody, CASP-1 Antibody, CASP1 nirs variant 1 Antibody, Caspase 1 Antibody, ICE Antibody, ICE-like protease Antibody, IL-1 beta-converting enzyme Antibody, IL-1BC Antibody, IL1BC Antibody, IL1BCE Antibody, p45 Antibody, IL1B-convertase Antibody, Interleukin-1 beta convertase Antibody


Specifications

Target
Human CASP1 / Caspase 1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bovine, Dog, Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
A synthetic peptide from the second quarter of human Caspase 1 protein.
Usage
Immunohistochemistry: LS-B3394 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3394 was determined to be 1:50.
Presentation
10 mM PBS, pH 7.4, Sodium Azide, BSA
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Images

Immunohistochemistry

Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3394 dilution 1:50.
Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3394 dilution 1:50.

Immunohistochemistry

Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3394 dilution 1:50.
Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3394 dilution 1:50.

Immunohistochemistry

Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3394 dilution 1:50.
Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3394 dilution 1:50.

Immunohistochemistry

Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3394 dilution 1:50.
Anti-Caspase 1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3394 dilution 1:50.

Requested From: United States
Date Requested: 9/23/2018

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