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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASP1 / Caspase 1 Antibody (aa371‑390, clone 14F468, Azide‑free) LS‑C368298
Caspase 1 antibody LS-C368298 is an unconjugated mouse monoclonal antibody to Caspase 1 (CASP1) from human and mouse. Validated for IHC and WB.
Catalog
Size
Price
LS-C368298-100
100 µg (0.5 mg/ml)
$365
Description
Caspase 1 antibody LS-C368298 is an unconjugated mouse monoclonal antibody to Caspase 1 (CASP1) from human and mouse. Validated for IHC and WB.
Target
Human CASP1 / Caspase 1
Host
Mouse
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Predicted
Chimpanzee, Gorilla (at least 90% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [14F468]
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free
Applications
  • IHC
  • IHC - Paraffin (1:10 - 1:500)
  • Western blot (0.5 - 2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
A synthetic peptide corresponding to amino acids 371-390 RKVRFSFEQPDGRAQMPTTE of human Caspase-1.
Epitope
aa371-390
Specificity
Human CASP1 / Caspase 1. The antibody will recognize full-length Caspase-1 and cleaved caspase-1 forms that retain amino acids 371-390 of the Caspase-1 protein.
Usage
Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Presentation
PBS. No stabilizing proteins added.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About CASP1 / Caspase 1
P29466 NM_001223 NP_001214.1

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Requested From: United States
Date Requested: 12/13/2018
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