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CAMKK2

calcium/calmodulin-dependent protein kinase kinase 2, beta

Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca2+ signals (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.

Gene Name: calcium/calmodulin-dependent protein kinase kinase 2, beta
Family/Subfamily: Protein Kinase , CAMKK
Synonyms: CAMKK2, CaM-kinase kinase 2, CaMKK beta, CAMKKB, CaM-KK beta, CaMKK, CAMKK beta protein, CaMKK 2, CaMKKbeta, KIAA0787, CaM KKB, CaM-kinase kinase beta, CaM-KK 2
Target Sequences: NM_006549 NP_006540.3 Q96RR4

☰ Filters
Antibodies (52)
Proteins (14)
ELISA Kits (4)
Custom (2)
Over-Expression Lysate (10)
Primary (52)
Recombinant (4)
Sandwich (2)
CAMKK2 (70)
Human (48)
Mouse (27)
Rat (14)
Bat (1)
Bovine (1)
Chimpanzee (3)
Guinea pig (4)
Horse (1)
Monkey (1)
Pig (1)
Rabbit (1)
Sheep (1)
IHC (18)
IHC-P (6)
WB (47)
ELISA (24)
ICC (3)
IF (4)
IP (7)
Peptide-ELISA (2)
rabbit (44)
mouse (8)
Product Group
IHCPlus (1)
IgG (35)
IgG1,k (6)
IgM,k (1)
monoclonal mc (7)
polyclonal pc (45)
96-Well Strip Plate (4)
APC Conjugated (4)
Azide-free (2)
Biotin Conjugated (6)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Unconjugated (26)
aa43-71 (7)
aa52-82 (7)
aa107-156 (4)
Internal (1)
Ser511 (1)
aa1-130 (1)
aa1-498 (1)
aa180-194 (1)
aa374-423 (1)
aa538-588 (1)
No (70)
Plasma (1)
Serum (1)
Tissue Homogenates (2)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (12)
Human (9)
293T Cells (5)
HEK 293 Cells (7)
Wheat Germ Extract (2)
Purified (1)
CAMKK2 Antibody - Western blot of lysates from U-87 MG cell line , human brain and rat cerebellum tissue lysate(from left to right), using Mouse Camkk2 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
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CAMKK2 Rabbit anti-Mouse Polyclonal (aa43-71) Antibody
Mouse, Rat, Human
WB
Unconjugated
400 µl/$393
CAMKK2 Antibody - IHC of paraffin-embedded U87 xenograft using CaMKK beta antibody at 1:500 dilution.
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CAMKK2 Rabbit anti-Human Polyclonal (aa1-498) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$450
CAMKK2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CAMKK2 Rabbit anti-Human Polyclonal (aa374-423) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
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CAMKK2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
CAMKK2 Antibody - 1:100 staining mouse spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CAMKK2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CAMKK2 Antibody - CAMKK2 / CAMKK antibody. IHC(P): Rat Brain Tissue.
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CAMKK2 Rabbit anti-Human Polyclonal (aa180-194) Antibody
Rabbit, Mouse, Guinea pig, Sheep, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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CAMKK2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$331
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CAMKK2 Rabbit anti-Human Polyclonal (aa52-82) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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CAMKK2 Rabbit anti-Human Polyclonal (aa52-82) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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CAMKK2 Rabbit anti-Human Polyclonal (aa52-82) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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CAMKK2 Rabbit anti-Human Polyclonal (aa52-82) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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CAMKK2 Rabbit anti-Human Polyclonal (aa52-82) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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CAMKK2 Rabbit anti-Human Polyclonal (aa52-82) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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CAMKK2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µl/$334; 100 µl/$397
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CAMKK2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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CAMKK2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
CAMKK2 Antibody - Immunohistochemistry image at a dilution of 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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CAMKK2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
CAMKK2 Antibody - Immunofluorescence staining of CAMKK2 in A431 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human CAMKK2 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
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CAMKK2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
CAMKK2 Antibody - Detection of Human CaMKK2 by Western Blot. Samples: Whole cell lysate (50 ug) from 293T, HeLa, and Jurkat cells. Antibodies: Affinity purified rabbit anti-CaMKK2 antibody used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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CAMKK2 Rabbit anti-Human Polyclonal (aa538-588) Antibody
Human
IHC, IP, WB
Unconjugated
10 µg/$295; 100 µl/$514
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CAMKK2 Mouse anti-Human Monoclonal (aa1-130) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$705
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CAMKK2 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IP, WB
Biotin Conjugated
100 µl/$904
CAMKK2 Antibody - Formalin-fixed and paraffin-embedded human prostate carcinoma tissue reacted with CAMKK2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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CAMKK2 Rabbit anti-Human Polyclonal (aa52-82) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
CAMKK2 Antibody - Immunohistochemical analysis of CaMKK beta staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CAMKK2 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
Select
CAMKK2 Rabbit anti-Mouse Polyclonal (aa43-71) Antibody
Mouse
ELISA, WB
Unconjugated
200 µl/$734
Select
CAMKK2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, WB
Unconjugated
100 µl/$786
Viewing 1-25 of 70 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).