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CALCOCO1 / CoCoa

calcium binding and coiled-coil domain 1

Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions.

Gene Name: calcium binding and coiled-coil domain 1
Synonyms: CALCOCO1, Calphoglin, PP13275, Sarcoma antigen NY-SAR-3, Cocoa, KIAA1536
Target Sequences: NM_020898 NP_065949.1 Q9P1Z2

☰ Filters
Antibodies (14)
Proteins (6)
Over-Expression Lysate (4)
Primary (14)
Recombinant (2)
CALCOCO1 / CoCoa (20)
Human (14)
Mouse (8)
Rat (5)
Bat (3)
Bovine (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Orangutan (3)
Rabbit (3)
IHC (7)
IHC-P (3)
WB (10)
ELISA (4)
ICC (1)
IF (3)
IP (2)
rabbit (14)
IgG (9)
polyclonal pc (14)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (11)
aa71-120 (4)
aa1-50 (1)
aa650-C-term (1)
No (20)
GST (1)
Myc-DDK (Flag) (5)
Human (4)
293T Cells (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
CALCOCO1 / CoCoa Antibody - Immunohistochemical analysis of CALCOCO1 staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
CALCOCO1 / CoCoa Antibody - Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
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CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
CALCOCO1 / CoCoa Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue.
Select
CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CALCOCO1 / CoCoa Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using CALCOCO1 Polyclonal Antibody at dilution of 1:50(×200)
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CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CALCOCO1 / CoCoa Antibody - Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
Select
CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CALCOCO1 / CoCoa Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using CALCOCO1 Polyclonal Antibody at dilution of 1:40(×200)
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CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal (aa650-C-term) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
CALCOCO1 / CoCoa Antibody - CALCOCO1 / CoCoa antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
WB
Unconjugated
100 µl/$424
CALCOCO1 / CoCoa Antibody - CALCOCO1 / CoCoa antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Gibbon, Orangutan, Human, Monkey
WB
HRP Conjugated
100 µl/$469
CALCOCO1 / CoCoa Antibody - CALCOCO1 / CoCoa antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Gibbon, Orangutan, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
CALCOCO1 / CoCoa Antibody - CALCOCO1 / CoCoa antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Gibbon, Orangutan, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Select
CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
Select
CALCOCO1 / CoCoa Rabbit anti-Human Polyclonal Antibody
Human
Unconjugated
100 µg/$341
CALCOCO1 / CoCoa Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
67.4 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
77.2 kDa
20 µg/$150
CALCOCO1 / CoCoa Protein - Purified recombinant protein CALCOCO1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
77.2 kDa
20 µg/$1,107
CALCOCO1 / CoCoa Protein - 12.5% SDS-PAGE of human CALCOCO1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
103.7 kDa
10 µg/$479; 25 µg/$670
CALCOCO1 / CoCoa Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
67.4 kDa
100 µg/$494
CALCOCO1 / CoCoa Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
77.2 kDa
100 µg/$494
Viewing 1-20 of 20 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).