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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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C5AR2 / GPR77 / C5L2 Antibody (N‑Terminus) LS‑C357900
C5L2 antibody LS-C357900 is an unconjugated rabbit polyclonal antibody to C5L2 (C5AR2 / GPR77) from human and primate. Validated for WB.
Catalog
Size
Price
LS-C357900-25
25 µg
$255
LS-C357900-100
100 µg
$355
Description
C5L2 antibody LS-C357900 is an unconjugated rabbit polyclonal antibody to C5L2 (C5AR2 / GPR77) from human and primate. Validated for WB.
Target
Human C5AR2 / GPR77 / C5L2
Host
Rabbit
Reactivity
Human, Primate (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1 - 3 µg/ml)
Immunogen
A recombinant protein fragment from the N-terminal region of human GPR77.
Epitope
N-Terminus
Specificity
Human C5AR2 / GPR77 / C5L2.
Usage
G protein receptors, also called GPRs, GPCRs, and seven-transmembrane domain receptors, are a large family of receptors with possibly over 800 members. These receptors sense stimuli outside, convey the signal across the cell membrane, and activate internal signal transduction pathways and cellular responses. GPR77 is involved in the complement system of the innate immune response and may signal through the beta-arrestin pathway, and possibly act as a decoy receptor. It is co-expressed with the C5a receptor on neutrophils and may modulate C5a1 activity.
Presentation
PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About C5AR2 / GPR77 / C5L2
Q9P296 NM_018485 NP_060955.1

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Western blot

GPR77 Antibody western blot with human samples
GPR77 Antibody western blot with human samples

Western blot

GPR77 Antibody western blot with human samples
GPR77 Antibody western blot with human samples

Western blot

GPR77 Antibody western blot with human samples
GPR77 Antibody western blot with human samples

Western blot

GPR77 Antibody western blot with human samples
GPR77 Antibody western blot with human samples

Requested From: United States
Date Requested: 12/13/2018
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