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BMP10

bone morphogenetic protein 10

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Gene Name: bone morphogenetic protein 10
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: BMP10, BMP-10, Bone morphogenetic protein 10
Target Sequences: NM_014482 NP_055297.1 O95393

Publications (1)

1
Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis. Nicola E Owen, Graeme J Alexander, Sambit Sen, Katherine Bunclark, Gary Polwarth, Joanna Pepke-Zaba, Anthony P Davenport, Nicholas W Morrell, Paul D Upton. EBioMedicine. 2020 Jun;56:102794. [Full Text Article] [PubMed:32454407] [PMC:PMC7248419] Related Antibodies: LS-C293026.

☰ Filters
Antibodies (59)
ELISA Kits (18)
Proteins (8)
Custom (2)
Over-Expression Lysate (2)
Primary (59)
Recombinant (6)
Sandwich (14)
Sandwich CLIA (2)
BMP10 (85)
Human (57)
Mouse (23)
Rat (16)
Bat (7)
Bovine (4)
Chicken (4)
Chimpanzee (3)
Dog (7)
Gibbon (6)
Guinea pig (6)
Hamster (4)
Horse (4)
Monkey (8)
Orangutan (3)
Pig (8)
Rabbit (8)
Zebrafish (3)
IHC (10)
IHC-P (3)
WB (52)
ELISA (12)
IF (1)
Neut (1)
Peptide-ELISA (1)
rabbit (47)
mouse (10)
goat (1)
rat (1)
Product Group
PathPlus Neuro (1)
IgG (30)
IgG2a (2)
monoclonal mc (10)
polyclonal pc (49)
11n14 (1)
MAB2926 (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (3)
96-Well Strip Plate (12)
APC (3)
APC Conjugated (4)
Azide-free (1)
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Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (4)
Preservative Free (1)
Unconjugated (24)
aa314-421 (9)
aa315-424 (8)
aa7-35 (7)
aa346-395 (4)
aa91-140 (4)
C-Terminus (1)
Internal (1)
aa20-313 (1)
aa282-327 (1)
aa317-424 (1)
aa84-94 (1)
aa86-96 (1)
No (84)
Yes (1)
Cell Culture Supernatants (3)
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Heparin Plasma (3)
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6His, N-terminus (1)
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Human (6)
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293T Cells (1)
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Biologically active (1)
BMP10 Antibody - Western blot analysis of BMP10 expression in HeLa (A); NIH3T3 (B); H9C2 (C) whole cell lysates.
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BMP10 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
BMP10 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
BMP10 Antibody - Western blot of recombinant BMP10 / BMP-10.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP10 Rabbit anti-Human Polyclonal (aa315-424) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
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BMP10 Goat anti-Human Polyclonal (aa20-313) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$930
BMP10 Antibody - Anti-BMP10 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Neuroscience
BMP10 Rabbit anti-Human Polyclonal (aa7-35) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$440
BMP10 Antibody - Western blot of recombinant BMP10 / BMP-10.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP10 Rabbit anti-Mouse Polyclonal (aa314-421) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
BMP10 Antibody - Western blot of recombinant BMP10 / BMP-10.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP10 Rabbit anti-Mouse Polyclonal (aa314-421) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
BMP10 Antibody - Western blot of Human MCF7. BMP10 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP10 Rabbit anti-Human Polyclonal (aa346-395) Antibody
Human
WB
Unconjugated
100 µl/$424
BMP10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
BMP10 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$863
BMP10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
250 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
BMP10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
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BMP10 Mouse anti-Human Monoclonal (aa317-424) (MAB2926) Antibody
Human
Neut, WB
Unconjugated
100 µg/$941; 500 µg/$1,795
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BMP10 Rabbit anti-Human Polyclonal (aa84-94) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
1 ml/$1,335
BMP10 Antibody - BMP10 antibody Western blot of Rat Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP10 Rabbit anti-Rat Polyclonal (aa91-140) Antibody
Rat
WB
Unconjugated
100 µl/$424
BMP10 Antibody - BMP10 antibody Western blot of Rat Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BMP10 Rabbit anti-Rat Polyclonal (aa91-140) (HRP) Antibody
Chicken, Zebrafish, Pig, Bat, Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Gibbon
WB
HRP Conjugated
100 µl/$469
BMP10 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$1,150
BMP10 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
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HEK 293 Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
24.4 kDa
2 µg/$268; 10 µg/$349
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BMP10 Rabbit anti-Human Polyclonal (aa7-35) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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BMP10 Rabbit anti-Human Polyclonal (aa7-35) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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BMP10 Rabbit anti-Human Polyclonal (aa7-35) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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BMP10 Rabbit anti-Human Polyclonal (aa7-35) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
BMP10 Antibody - Immunohistochemistry image of paraffin-embedded human breast cancer at a dilution of 1:100
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BMP10 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
BMP10 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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BMP10 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 85 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).