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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BLM Antibody (aa100‑150) LS‑C287049
BLM antibody LS-C287049 is an unconjugated goat polyclonal antibody to human BLM. Validated for IP, PLA and WB.
Antibody
Catalog
Size
Price
LS-C287049-100
100 µl (1 mg/ml)
$395

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Product Description

BLM antibody LS-C287049 is an unconjugated goat polyclonal antibody to human BLM. Validated for IP, PLA and WB.

Specifications

Target
Human BLM
Synonyms
BLM, Bloom syndrome, Bloom syndrome protein, BS, Bloom's syndrome protein, DNA helicase, RecQ-like type 2, RECQ2, RECQL2, RECQL3, RecQ protein-like 3
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:1000 - 1:10000)
  • Immunoprecipitation (1 - 4 µg/mg lysate)
  • Proximity Ligation Assay (1:1000 - 1:20000)
Epitope
aa100-150
Specificity
Region between residues 100 and 150 of human Bloom Syndrome using the numbering given in entry NP_000048.1 (GeneID 641).
Manufacturer
Bethyl Laboratories, Inc.
Presentation
Tris-citrate/phosphate buffer, pH 7-8, 0.09% sodium azide.
Storage
Store at 2°C to 8°C for up to 1 year.
Restrictions
For research use only.
About BLM
Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE). P54132 NM_000057 NP_000048.1


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Requested From: United States
Date Requested: 11/13/2018

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