Human BIRC8 / ILP2
BIRC8 | HILP2 | ILP-2 | ILP2 | IAP-like protein 2
(tested or 100% immunogen sequence identity)
Synthetic peptide TGYEARLITFGT corresponding to amino acids 2-13 of human ILP-2. Percent identity by BLAST analysis: Human, Chimpanzee (100%); Gorilla (92%).
Recognizes Baculoviral IAP repeat-containing protein 8 also known as inhibitor of apoptosis protein- like protein 2, ILP-2 or BIRC8. ILP-2 is a 236 amino acid ~27 kD cytoplasmic protein belonging to the IAP family of apoptosis inhibitors and is expressed solely in the testis in normal tissue. ILP-2 is reported to bind to caspase 9 and is thought to protect against apoptosis mediated by BAX.